Results 191 to 200 of about 1,488,092 (350)
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Digital twin-based machine learning framework for predicting nonlinear seismic response of reinforced concrete shear walls using analytical data. [PDF]
Sci RepKuria KK, Kegyes-Brassai O.
europepmc +1 more source
Why Does the Yield Curve Predict GDP Growth? The Role of Banks
, 2023 Camelia Minoiu +2 more
openalex +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Study on viscosity and yield stress of magnetic fluid applied to low temperature magnetic fluid seal. [PDF]
Sci RepLiu J, Li D.
europepmc +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Convolutional Neural Networks for Estimation of Uniaxial Tensile Test Equivalent Properties from Small Punch Test. [PDF]
Materials (Basel)Kaliciak M, Uhl T, Nowak M.
europepmc +1 more source
How Far Can the Long-Run Risk Model with Durable Goods Explain the Variation of the Yield Curve?
, 2023 Ryoichi Ikeda, Yoske Iagarashi
openalex +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source