Engineering Escherichia coli for high-yield production of ectoine
Green Chemical Engineering, 2023 Ectoine is a natural macromolecule protector and synthesized by some extremophiles. It provides protections against radiation-mediated oxidative damages and is widely used as a bioactive ingredient in pharmaceutics and cosmetics.
Daoan Wang +4 more
doaj +2 more sources
Metabolic engineering for high yield synthesis of astaxanthin in Xanthophyllomyces dendrorhous [PDF]
Microbial Cell Factories, 2021 Astaxanthin is a carotenoid with a number of assets useful for the food, cosmetic and pharmaceutical industries. Nowadays, it is mainly produced by chemical synthesis.
Alejandro Torres-Haro +3 more
doaj +2 more sources
Reverse Engineering the Yield Curve [PDF]
, 1994 Prices of riskfree bonds in any arbitrage-free environment are governed by a pricing kernel: given a kernel, we can compute prices of bonds of any maturity we like. We use observed prices of multi-period bonds to estimate, in a log-linear theoretical setting, the pricing kernel that gave rise to them.
David Backus, Stanley E. Zin
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Engineering Escherichia coli for high-yield geraniol production with biotransformation of geranyl acetate to geraniol under fed-batch culture [PDF]
Biotechnology for Biofuels, 2016 BackgroundGeraniol is an acyclic monoterpene alcohol, which exhibits good prospect as a gasoline alternative. Geraniol is naturally encountered in plants at low concentrations and an attractive target for microbial engineering.
Wei Liu +8 more
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Engineering DYRK1A overdosage yields Down syndrome-characteristic cortical splicing aberrations
Neurobiology of Disease, 2010 Down syndrome (DS) associates with impaired brain functions, but the underlying mechanism(s) are yet unclear. The "gene dosage" hypothesis predicts that in DS, overexpression of a single gene can impair multiple brain functions through a signal amplification effect due to impaired regulatory mechanism(s).
Debra Toiber +5 more
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A process engineering approach to increase organoid yield
Development, 2017 Temporal manipulation of the in vitro environment and growth factors can direct differentiation of human pluripotent stem cells into organoids, aggregates with multiple tissue-specific cell types and three-dimensional structure mimicking native organs. A mechanistic understanding of early organoid formation is essential for improving the robustness of ...
Natasha Arora +9 more
semanticscholar +3 more sources
Emerging engineering principles for yield improvement in microbial cell design
Computational and Structural Biotechnology Journal, 2012 Metabolic Engineering has undertaken a rapid transformation in the last ten years making real progress towards the production of a wide range of molecules and fine chemicals using a designed cellular host.
Santiago Comba +2 more
doaj +5 more sources
Phage-assisted evolution and protein engineering yield compact, efficient prime editors
Cell, 2023 Jordan L. Doman +16 more
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Engineering Curcumin Biosynthesis in Poplar Affects Lignification and Biomass Yield
Frontiers in Plant Science, 2022 Lignocellulosic biomass is recalcitrant toward deconstruction into simple sugars mainly due to the presence of lignin. By engineering plants to partially replace traditional lignin monomers with alternative ones, lignin degradability and extractability ...
Barbara De Meester +17 more
doaj +4 more sources
Atomically engineered interfaces yield extraordinary electrostriction
Nature, 2022 Electrostriction is a property of dielectric materials whereby an applied electric field induces a mechanical deformation proportional to the square of that field. The magnitude of the effect is usually minuscule (
Haiwu Zhang +15 more
openaire +4 more sources