Results 301 to 310 of about 6,883,757 (381)

Analysis of Yield Rate in Single Crystal Casting Process Using an Engineering Simulation Model

, 2003
Hisao Esaka, Manabu Tamura, Kei Shinozuka   +2 more
openalex   +2 more sources

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

FEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli, Andrea Spinaci, Cui Chang, Rosaria Volpini, Catia Lambertucci, Matteo Landriscina, Vincenza Conteduca, Consuelo Amantini, Cristina Aguzzi, Laura Zeppa, Martina Giangrossi, Laura Soverchia, Matteo Santoni, Massimo Nabissi, Giorgio Santoni, Carlo Polidori   +15 more
wiley   +1 more source

Investigation of the Microstructural Evolution and Mechanical Properties of the AlCoCrFeNi_2.1 EHEA Fabricated by Additive Manufacturing Assisted by Heat Treatment. [PDF]

Materials (Basel)
Zhang X, Feng W, Jia F, Liu W, Wang J, Zhu L, Cai Y.   +6 more
europepmc   +1 more source

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

FEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei, Zhanbiao Liu, Jingjing Shi, Qian Jin, Wenqian Chen, Xuejun Chen, Liqin Li, Hui Chen   +7 more
wiley   +1 more source

Crops under stress: can we mitigate the impacts of climate change on agriculture and launch the 'Resilience Revolution'? [PDF]

Philos Trans R Soc Lond B Biol Sci
Mittler R, Karlova R, Bassham DC, Lawson T.   +3 more
europepmc   +1 more source

Machine Learning Approaches for Predicting Maize Biomass Yield: Leveraging Feature Engineering and Comprehensive Data Integration

Maryam Abbasi, Paulo Váz, José Silva, Pedro Martins   +3 more
openalex   +1 more source

Downregulation of O‐GlcNAcylation enhances etoposide‐induced p53‐mediated apoptosis in HepG2 human liver cancer cells

FEBS Open Bio, EarlyView.
Etoposide, a topoisomerase II inhibitor, reduces O‐GlcNAcylation in HepG2 liver cancer cells. Further inhibition of O‐GlcNAc transferase by OSMI‐1 enhanced etoposide‐induced apoptosis, lowering the IC50 for viability and increasing the EC50 for cytotoxicity.
Jaehoon Lee, Gi‐Bang Koo, Jihye Park, Byung‐Cheol Han, Mijin Kwon, Seung‐Ho Lee   +5 more
wiley   +1 more source

Influence of Deformation Degree on Microstructural Evolution and Tensile Behavior of TiB-Reinforced IMI834 Composites. [PDF]

Materials (Basel)
Wang B, Liu M, Zhao Z, Li J, Fan M, Li Z.   +5 more
europepmc   +1 more source

Enhancing quality and yield of recombinant secretory IgA antibodies in Nicotiana benthamiana by endoplasmic reticulum engineering

Kathrin Göritzer, Stanislav Melnik, Jennifer Schwestka, Elsa Arcalís, Margit Drapal, Paul D. Fraser, Julian K‐C., Eva Stöger   +7 more
openalex   +1 more source

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

FEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren, Ileana Cristea, Thomas Stevenson, Endy Spriet, Per Morten Knappskog, Stig Ove Bøe, Harald Kranz, Sushma N. Grellscheid, Eyvind Rødahl   +8 more
wiley   +1 more source