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Bad Engineering Yields Even Worse Lawsuits

Journal of Performance of Constructed Facilities, 2001
A civil engineer performed a condition evaluation of an eight-story building of approximately 1,500 m2 (16,000 ft2) per floor constructed in 1909 in downtown Milwaukee. Subsequent to the evaluation, a failed real estate transaction along with poor forensic engineering investigation and incomplete testing led to a lawsuit filed against the civil ...
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High-yield porphyrin production through metabolic engineering and biocatalysis

Nature Biotechnology
Porphyrins and their derivatives find extensive applications in medicine, food, energy and materials. In this study, we produced porphyrin compounds by combining Rhodobacter sphaeroides as an efficient cell factory with enzymatic catalysis. Genome-wide CRISPRi-based screening in R. sphaeroides identifies hemN as a target for improved coproporphyrin III
Haihong Chen   +28 more
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A previously unidentified sugar transporter for engineering of high-yield Streptomyces

Applied Microbiology and Biotechnology
Sugar transporters have significant contributions to regulate metabolic flux towards products and they are general potential targets for engineering of high-yield microbial cell factories. Streptomyces, well-known producers of natural product pharmaceuticals, contain an abundance of sugar transporters, while few of them are well characterized and ...
Zhuoxu Dong   +6 more
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Yield Engineering

2007
Manoj Sachdev, José Pineda de Gyvez
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Human TRPV4 engineering yields an ultrasound-sensitive actuator for sonogenetics

AbstractSonogenetics offers non-invasive and cell-type specific modulation of cells genetically engineered to express ultrasound-sensitive actuators. Finding an ion channel to serve as sonogenetic actuator it critical for advancing this promising technique. Here, we show that ultrasound can activate human TRP channel hTRPV4.
Lu, Zhao   +10 more
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Engineered bacteria could boost corn yields

Chemical & Engineering News, 2022
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YIELD IN CHEMICAL REACTOR ENGINEERING

Industrial & Engineering Chemistry, 1966
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