Results 111 to 120 of about 1,990,499 (312)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Richard O. Mason, Sue A. Conger
openaire +2 more sources
Variability in meteorological patterns presents significant challenges to crop production consistency and yield stability. Meteorological influences on corn and soybean grain yields were analyzed over an 18-year period at a long-term experiment in ...
John R. Teasdale, Michel A. Cavigelli
doaj +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
HOTEL YIELD MANAGEMENT TECHNOLOGIES
The article deals with the issue of hotel development stabilization. The author describes Yield Management (Revenue Management) as especially relevant for the hotel industry, identifies the flaws in the current practices, provides details of strategic revenue management tools, dwells on the concept of yield management process and specifies the features
openaire +1 more source
Canola-Wheat Rotation versus Continuous Wheat for the Southern Plains [PDF]
Crop rotations are not common in the wheat belt of the Southern Plains. After years of continuous wheat, weeds have become increasingly difficult and expensive to manage.
Duke, Jason C. +3 more
core +1 more source
Analysis of the interactions of shade trees on coffee leaf diseases and coffee yield in complex agroforestry systems [PDF]
In complex coffee-based agroforestry, quantifying interactions within the agrosystem that impact on coffee disease regulation and on coffee yield is a major stake to design sustainable cropping systems.
Allinne, Clémentine +6 more
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Sunflower Planting Date Trial [PDF]
Sunflowers are being grown in the Northeast for their potential to add value to a diversified operation as fuel, feed, fertilizer, and an important rotational crop.
Calderwood, Lily +5 more
core +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source

