Results 131 to 140 of about 1,990,499 (312)

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Economic analysis of site-specific wheat management with respect to grain quality and separation of the different quality fractions [PDF]

open access: yes
The paper analyzes site-specific and uniform management options for wheat production with respect to grain quality. Besides site-specific fertilization the economic potential of segregation of different grain qualities is the subject of this paper. Yield
Gandorfer, Markus   +3 more
core   +1 more source

Pacific bonito management information document [PDF]

open access: yes, 1980
Management of Pacific bonito in California is examined in this Management Information Document by a State-Federal team of scientists. Abundance of Pacific bonito in southern California has fallen dramatically between the 1963-1969 period and the 1974 ...
Collins, R.   +4 more
core  

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Nonlinear Term Structure Dependence: Copula Functions, Empirics, and Risk Implications [PDF]

open access: yes
This paper documents nonlinear cross-sectional dependence in the term structure of U.S. Treasury yields and points out risk management implications. The analysis is based on a Kalman filter estimation of a two-factor affine model which specifies the ...
Alexander Szimayer   +2 more
core  

Management affects nitrate leaching from organic farms [PDF]

open access: yes, 2013
Management decisions significantly affect nitrate-N leaching (N-leaching) from comparable organic fields. The main concern is field management during autumn and themanagement of grass leys.
Askegaard, Margrethe, Eriksen, J.
core  

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

The maximum economic yield management of an age-structured salmon population [PDF]

open access: yes
This chapter develops a sustainable economic yield harvesting model for the wild Atlantic salmon (Salmo salar) where the population comprises different age classes. It is shown that the weight–fecundity relationship of the spawning population, comprising
Anders Skonhoft
core  

Sunflower Planting Date x Variety Trial [PDF]

open access: yes, 2016
Sunflowers are being grown in the Northeast for their potential to add value to a diversified operation as fuel, feed, fertilizer, and an important rotational crop.
Brigham, Nate   +4 more
core   +1 more source

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