Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Phenological optimization of late reproductive phase for raising wheat yield potential in irrigated mega-environments. [PDF]
Hu P +4 more
europepmc +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Preliminary Study on Growth and Yield Potential of Ten Elite Lines of Quinoa (Chenopodium quinoa) Cultivated under Varying Sowing Dates. [PDF]
Asif A +14 more
europepmc +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Retraction: Genome-wide association mapping of bread wheat genotypes for sustainable food security and yield potential under limited water conditions. [PDF]
PLOS ONE Editors.
europepmc +1 more source
MOVING FROM UNIFORM TO VARIABLE FERTILIZER RATES ON IOWA CORN: EFFECTS ON RATES AND RETURNS [PDF]
This study develops a model based on the yield potential of various soil types in 12 Iowa counties to estimate the potential value of switching from uniform to variable fertilizer rates.
Babcock, Bruce A., Pautsch, Gregory R.
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
A 14-3-3 modulator of seed weight and quality for unlocking the yield potential of soybean. [PDF]
Li B +9 more
europepmc +1 more source
Normalization method for canopy temperature as an indirect indicator of yield potential in wheat breeding programs. [PDF]
Ohnishi S, Kasuya M, Sonoda T, Jinno H.
europepmc +1 more source

