Results 101 to 110 of about 1,208,308 (295)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Genetic control of soybean (Glycine max) yield in the absence and presence of the Asian rust fungus (Phakopsora pachyrhizi)

Genetics and Molecular Biology, 2008
Soybean is one of the most important crops in Brazil and continuously generates demands for production technologies, such as cultivars resistant to diseases. In recent years, the Asian rust fungus (Phakopsora pachyrhizi Syd. & P.
Aliny Simony Ribeiro, José Francisco Ferraz de Toledo, Carlos Alberto Arrabal Arias, Cláudia Vieira Godoy, Rafael Moreira Soares, José Ubirajara Vieira Moreira, Pedro Henrique Braga Pierozzi, Maria Celeste Gonçalves Vidigal, Marcelo Fernandes de Oliveira   +8 more
doaj   +1 more source

Wheat yield forecasts using LANDSAT data [PDF]

Several considerations of winter wheat yield prediction using LANDSAT data were discussed.
Colwell, J. E., Nalepka, R. F., Rice, D. P.   +2 more
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Wheat productivity estimates using LANDSAT data [PDF]

The author has identified the following significant results. Large area LANDSAT yield estimates were generated. These results were compared with estimates computed using a meteorological yield model (CCEA).
Bresnahan, P. A., Colwell, J. E., Nalepka, R. F., Rice, D. P.   +3 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

The Promise of Prediction Markets [PDF]

Prediction markets are markets for contracts that yield payments based on the outcome of an uncertain future event, such as a presidential election. Using these markets as forecasting tools could substantially improve decision making in the private and ...
Arrow, Kenneth J., Forsythe, Robert, Gorham, Michael, Hahn, Robert W., Hanson, Robin, Ledyard, John O., Levmore, Saul, Litan, Robert E., Milgrom, Paul, Nelson, Forrest D., Neumann, George R., Ottaviani, Marco, Schelling, Thomas C., Shiller, Robert J., Smith, Vernon L., Snowberg, Erik, Sunstein, Cass R., Tetlock, Paul C., Tetlock, Philip E., Varian, Hal R., Wolfers, Justin, Zitzewitz, Eric   +21 more
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source