Results 131 to 140 of about 321,230 (311)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Prediction of Synthesis Yield of Polymethoxy Dibutyl Ether Under Small Sample Conditions

Molecules
In chemical reaction processes, yield prediction frequently faces challenges, such as multi-variable coupling, significant nonlinearity, and the limited accuracy of traditional mechanistic models.
Xue Wang, Linyu Lu, Qiuxin Ma, Hongyan Shang, Lanyi Sun   +4 more
doaj   +1 more source

Accuracy of predicting milk yield from alternative milk recording schemes

, 2005
peer-reviewedThe effect of reducing the frequency of official milk recording and the number of recorded samples per test-day on the accuracy of predicting daily yield and cumulative 305-day yield was investigated.
Cromie, A. R., Veerkamp, Roel F., P. Dillon, D. P. Berry, A. R. Cromie, Rath, M., Dillon, Pat, Berry, D.P., M. Rath, Olori, V. E., Rath, Myles V, Dilon, P., Olori, V.E., V. E. Olori, Veerkamp, R.F., R. F. Veerkamp, Cromie, A.R., Berry, Donagh   +17 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Artificial intelligence and Multispectral Imaging Technologies for Assessing Climate Impact on Maize Yield: A Literature Review

Maǧallaẗ al-baṣraẗ al-ʻulūm al-zirāʻiyyaẗ
Maize production in Central America and Mexico is particularly susceptible to climate variability, especially the El Niño-Southern Oscillation (ENSO), which causes drought and irregular rainfall.
Carlos R. Martínez- Martínez, Felipe Machorro- Ramos, Laura Rodríguez- Peralta   +2 more
doaj   +1 more source

Pre-harvest Forecasting of County Wheat Yield and Wheat Quality Conditional on Weather Information

Wheat regression models that account for the effect of weather are developed to forecast wheat yield and quality. Spatial lag effects are included. Wheat yield, protein, and test weight level are strongly influenced by weather variables.
Kenkel, Philip L., Lee, Byoung-Hoon, Brorsen, B. Wade   +2 more
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Development of a 2D Image-Based Rice Panicle-Level Yield Prediction Framework Using Image-Based Reconstruction Technique

Agronomy
Asian countries, which account for more than 60% of global rice consumption, are expanding the adoption of precision agriculture technology using image sensors to increase the profitability of rice production.
Daehong Kim, Hyeongjun Lim, Sojung Kim
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Field-Scale Prediction of Winter Wheat Yield Using Satellite-Derived NDVI

Agronomy
This study evaluated the potential of Sentinel-2-derived NDVI (Normalized Difference Vegetation Index) for predicting within-field variability of winter wheat grain yield in central Lithuania during the 2024 growing season.
Edyta Okupska, Antanas Juostas, Dariusz Gozdowski, Elżbieta Wójcik-Gront   +3 more
doaj   +1 more source