Results 91 to 100 of about 292,995 (264)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Sensor-Based Yield Prediction in Durum Wheat Under Semi-Arid Conditions Using Machine Learning Across Zadoks Growth Stages

Remote Sensing
Yield prediction in wheat cultivated under semi-arid climatic conditions is gaining increasing importance for sustainable production strategies and decision support systems.
Süreyya Betül Rufaioğlu, Ali Volkan Bilgili, Erdinç Savaşlı, İrfan Özberk, Salih Aydemir, Amjad Mohamed Ismael, Yunus Kaya, João P. Matos-Carvalho   +7 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Development of a 2D Image-Based Rice Panicle-Level Yield Prediction Framework Using Image-Based Reconstruction Technique

Agronomy
Asian countries, which account for more than 60% of global rice consumption, are expanding the adoption of precision agriculture technology using image sensors to increase the profitability of rice production.
Daehong Kim, Hyeongjun Lim, Sojung Kim
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Enhancing AquaCrop model precision for accurate simulation of sweet potato and taro landraces

Frontiers in Sustainable Food Systems
Neglected and underutilised crop species (NUS) such as orange-fleshed sweet potato (OFSP) and taro are nutrient-dense, climate-resilient crops with high potential to diversify food systems.
Thando Lwandile Mthembu, Richard Kunz, Tafadzwanashe Mabhaudhi, Tafadzwanashe Mabhaudhi, Tafadzwanashe Mabhaudhi, Tafadzwanashe Mabhaudhi, Shaeden Gokool   +6 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Prediction of Synthesis Yield of Polymethoxy Dibutyl Ether Under Small Sample Conditions

Molecules
In chemical reaction processes, yield prediction frequently faces challenges, such as multi-variable coupling, significant nonlinearity, and the limited accuracy of traditional mechanistic models.
Xue Wang, Linyu Lu, Qiuxin Ma, Hongyan Shang, Lanyi Sun   +4 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Artificial intelligence and Multispectral Imaging Technologies for Assessing Climate Impact on Maize Yield: A Literature Review

Maǧallaẗ al-baṣraẗ al-ʻulūm al-zirāʻiyyaẗ
Maize production in Central America and Mexico is particularly susceptible to climate variability, especially the El Niño-Southern Oscillation (ENSO), which causes drought and irregular rainfall.
Carlos R. Martínez- Martínez, Felipe Machorro- Ramos, Laura Rodríguez- Peralta   +2 more
doaj   +1 more source