Results 41 to 50 of about 287,762 (312)

Dexamethasone for Chemotherapy‐Induced Nausea and Vomiting Prevention in Pediatric Patients: International Consensus

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An international Delphi panel of experts developed consensus statements to delineate the circumstances where the risks of dexamethasone as an antiemetic do and do not outweigh its benefits. Procedure Experts in supportive care of pediatric patients were invited to participate.
Negar Shavandi   +20 more
wiley   +1 more source

Extracellular vesicles yield predictive pre‐eclampsia biomarkers [PDF]

open access: yesJournal of Extracellular Vesicles, 2017
ABSTRACTCirculating extracellular vesicles (EVs) such as cholera toxin B chain (CTB)‐ or annexin V (AV)‐binding EVs were previously shown to be rich sources of biomarkers. Here we test if previously identified pre‐eclampsia (PE) candidate biomarkers, TIMP‐1 in CTB‐EVs (CTB‐TIMP) and PAI‐1 in AV‐EVs (AV‐PAI) complement plasma PlGF in predicting PE in a ...
Kok Hian Tan   +6 more
openaire   +3 more sources

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine   +14 more
wiley   +1 more source

Quantitative self-assembly prediction yields targeted nanomedicines [PDF]

open access: yesNature Materials, 2018
Development of targeted nanoparticle drug carriers often requires complex synthetic schemes involving both supramolecular self-assembly and chemical modification. These processes are generally difficult to predict, execute, and control. We describe herein a targeted drug delivery system that is accurately and quantitatively predicted to self-assemble ...
Yosi Shamay   +20 more
openaire   +3 more sources

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

Assessing Maize Yield Spatiotemporal Variability Using Unmanned Aerial Vehicles and Machine Learning

open access: yesGeomatics
Optimizing the prediction of maize (Zea mays L.) yields in smallholder farming systems enhances crop management and thus contributes to reducing hunger and achieving one of the Sustainable Development Goals (SDG 2—zero hunger). This research investigated
Colette de Villiers   +4 more
doaj   +1 more source

Winter Wheat Yield Prediction Using Convolutional Neural Networks from Environmental and Phenological Data [PDF]

open access: green, 2021
Amit Kumar Srivast   +7 more
openalex   +1 more source

Lettuce Yield Prediction

open access: yesInternational journal of electrical and computer engineering systems
Indoor aeroponic vertical farming systems have revolutionized agriculture by allowing efficient use of space and resources, eliminating the need for soil. These systems improve crop productivity and growth rates. However, accurately predicting lettuce yield in aeroponic environments remains a complex task due to the intricate interactions between ...
Gowtham Rajendiran, Jebakumar Rethnaraj
openaire   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

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