Results 131 to 140 of about 409,778 (302)

Dynamic Risk Profile of the US Term Structure by Wavelet MRA [PDF]

A careful examination of interest rate time series from different U.S. Treasury maturities by Wavelet Multiresolution Analysis (MRA) suggests that the first differences of the term structure of interest rate series are periodic or, at least, cyclic, non ...
CORNELIS A. LOS, SUTTHISIT JAMDEE
core  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Debt Dilution and Maturity Structure of Sovereign Bonds [PDF]

We develop a dynamic model of sovereign default and renegotiation to study how expectations of default and debt restructuring in the near future affect the ex ante maturity structure of sovereign debts.
Ran Bi
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Effects of flowering behavior and pod maturity synchrony on yield of mungbean [Vigna radiata (L.) Wilczek]. [PDF]

, 2011
A number of experiments were set up to assess the flower production and flowering pattern in synchrony with pod maturity and seed yield in twelve mungbean genotypes.
Ali Fakir, Md Solaiman, Hakim, M. A., Islam, M. Monirul, Juraimi, Abdul Shukor, Mondal, Mohd Monjurul Alam, Shamsuddoha, A. T. M.   +5 more
core  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Genetic Variability and Relative Importance of Nine Phenological and Physiological Characters Studied in Spring Wheat (Triticum aestivum L.) [PDF]

, 2015
Experiment was designed to establish a more definitive relationship of phenological and physiological traits with yield in wheat using twenty five spring wheat genotypes.
Abul Awlad Khan
core   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Incomplete markets, liquidation risk and the term structure of interest rates [PDF]

We construct a general equilibrium model with incomplete markets and borrowing constraints, in order to study the term structure of real interest rates.
Edouard Challe, François Le Grand, Xavier Ragot   +2 more
core   +3 more sources

Optimizing crop geometry for enhanced growth and yield of soybean [Glycine max L. (Merrill)] maturity groups in western Ethiopia

Agrosystems, Geosciences & Environment
Increasing soybean [Glycine max L. (Merrill)] productivity relies heavily on optimizing crop geometry, encompassing both inter‐ and intra‐row spacing. This crucial agronomic practice directly impacts the productivity of soybean crops, making it vital for
Alemayehu Dabessa, Feyera Takele, Chala Debala, Zerihun Abebe   +3 more
doaj   +1 more source

A new framework for yield curve, output and inflation relationships [PDF]

, 2005
This article develops a theoretically-consistent and easy-to-apply framework for interpreting, investigating, and monitoring the relationships between the yield curve, output, and inflation.
Krippner, Leo
core   +1 more source