Results 191 to 200 of about 90,068,201 (300)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Validating superior maize hybrids in all India coordinated trials using REMATTOOL-R: a decision support approach. [PDF]

Front Plant Sci
Neelam S, Bhoga J, Bellamkonda J, Dharavath B, Choudhary M, Kumar P, Phagna RK, Singh SB, Appavoo D, Jat HS.   +9 more
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Unlocking wheat yield potential through evaluation of high-performing hybrid lines in semiarid conditions of northern Pakistan. [PDF]

PLoS One
Khan HA, Arif M, Zhang S, Munsif F, Lou H, Gao Y, Ullah B, Anjum MM, Khan M, Saeed B.   +9 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

The Influence of Bond Ratings, Debt to Equity Ratio, and Bond Maturity on Bond Yield to Maturity in Manufacturing Companies Listed on The Indonesia Stock Exchange in 2022

The aim of this research is to analyze the influence of bond ratings, debt to equity ratio, and bond maturity on bond yield to maturity in manufacturing companies listed on the Indonesia Stock Exchange in 2022.
Nadeak, Angelyna
core  

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Investigating the Role of MicroRNA396 (miR396) Gene in Regulating Wheat Yield and Grain Nitrogen Concentration. [PDF]

Plants (Basel)
Yin Y, Yu Y, Ma Z, Wang Y, Yang Z, Li M, Zhu M, Li D, Gou M, Mu X.   +9 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Yield Stability and Adaptability of Black Soybean Line BSCM41 Support Bi-Directional Seed Rotation System in Northeast Thailand. [PDF]

Plants (Basel)
Phosuk K, Chinnarat J, Monkham T, Sanitchon J, Khodphuwiang J, Reewarabundit S, Chankeaw S.   +6 more
europepmc   +1 more source