Results 101 to 110 of about 75,211 (286)

A common founding clone with TP53 and PTEN mutations gives rise to a concurrent germ cell tumor and acute megakaryoblastic leukemia [PDF]

open access: yes, 2016
We report the findings from a patient who presented with a concurrent mediastinal germ cell tumor (GCT) and acute myeloid leukemia (AML). Bone marrow pathology was consistent with a diagnosis of acute megakaryoblastic leukemia (AML M7), and biopsy of an ...
Demeter, Ryan T   +12 more
core   +2 more sources

New Hydrazone Derivatives Featuring Isatin and Piperazine Moieties: Synthesis, Cytotoxicity Evaluation, and Molecular Modeling Studies

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT In this study, ten novel compounds (IPH1–IPH10) were designed by integrating three pharmacophores (isatin, piperazine, and hydrazone) commonly found in the molecular structures of anticancer agents. The target molecules were obtained by the reaction of in‐house prepared 4‐(4‐(pyridin/pyrimidin‐2‐yl)piperazin‐1‐yl)benzohydrazide with various ...
Semiha Köprü   +3 more
wiley   +1 more source

Primary yolk sac tumor of seminal vesicle: a case report and literature review

open access: yesWorld Journal of Surgical Oncology, 2012
Background Yolk sac tumor (endodermal sinus tumor) is a rare malignant germ cell tumor arising in the testis or ovary. Extragonadal yolk sac tumor is even rarer and has only been described in case reports.
Yao Xu-Dong   +3 more
doaj   +1 more source

Deciphering infant mortality. Part 1: empirical evidence

open access: yes, 2016
This paper is not (or at least not only) about human infant mortality. In line with reliability theory, "infant" will refer here to the time interval following birth during which the mortality (or failure) rate decreases.
Berrut, Sylvie   +3 more
core  

Assessing the hidden risks of non‐thermal processing: Ultrasound‐induced toxicity of cashew apple juice in a zebrafish model

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract Background High‐intensity ultrasound is widely advocated for the preservation of liquid foods; however, the potential formation or release of toxic compounds during processing remains under‐investigated. This study evaluated the toxicological profile of cashew apple juice processed by high‐intensity ultrasound (1250, 1875, and 2500 W;L⁻¹ ...
Thaiz Batista Azevedo Rangel Miguel   +5 more
wiley   +1 more source

Relevance of navel quality of day-old chick on organ development, initial performance, and bacterial presence

open access: yesPoultry Science
This study aimed to evaluate effects of day-old chick navel quality on the absorption of the residual yolk sac, visceral development, macroscopic organ alterations, yolk sac bacterial presence and performance of broilers up to 14 d of age. A total of 372
Mariana Cristina Vieira   +10 more
doaj   +1 more source

Reproductive cycle, nutrition and growth of captive blue spotted stingray, Dasyatis kuhlii (Dasyatidae) [PDF]

open access: yes
At Burgers' Ocean 7 male and 3 female blue spotted stingrays, Dasyatis kuhlii were born over a period of 4.5 years. This paper describes the experiences of the captive breeding results of this species. The first two young died within 2 days of birth. One
Janse, M., Schrama, J.W.
core   +3 more sources

Macrophages in endocrine glands, with emphasis on pancreatic islets [PDF]

open access: yes, 2016
We review here the macrophages found in endocrine tissues, placing emphasis on those residing in the islets of Langerhans of the pancreas. The islets represent the endocrine organ where macrophages have been examined in great detail and where our own ...
Unanue, Emil R
core   +2 more sources

Management of germ cell tumors in children: Approaches to cure [PDF]

open access: yes, 2002
The introduction of cisplatinum chemotherapy and current advances in the surgical treatment have resulted in a dramatic improvement of the prognosis of children with malignant germ cell tumors (GCT).
Calaminus, G.   +4 more
core   +1 more source

Histiocytosis development and clinical variation through the lens of genomics

open access: yesThe Journal of Pathology, EarlyView.
Abstract Histiocytic neoplasms are rare haematologic diseases characterised by clonal expansions of cells with a monocyte, macrophage or dendritic cell phenotype. Their clinical manifestations are diverse, ranging from indolent lesions to aggressive systemic disease.
Paul G Kemps   +3 more
wiley   +1 more source

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