Results 41 to 50 of about 170,507 (251)

Antibiotic–Polycationic Peptide Conjugation as an Effective Strategy to Overcome Daptomycin Resistance

Advanced Therapeutics, EarlyView.
Antimicrobial resistance necessitates the development of new antibiotics with “resistance‐breaking” properties. In this study, conjugation of polycationic peptides is proven to represent a versatile strategy for the fast and affordable reactivation of daptomycin.
Sari Rasheed, Florian Umstätter, Eric Mühlberg, Barbro Beijer, Tobias Hertlein, Karel D. Klika, Christian Kleist, Julia Werner, Cornelius Domhan, Mara Bingel, Anna Müller, Marvin Rausch, Stefan Zimmermann, Knut Ohlsen, Uwe Haberkorn, Marcus Koch, Markus Bischoff, Tanja Schneider, Rolf Müller, Jennifer Herrmann, Walter Mier, Philipp Uhl   +21 more
wiley   +1 more source

Cystathionine β‐synthase is required for oocyte quality by ensuring proper meiotic spindle assembly

Cell Proliferation, Volume 55, Issue 12, December 2022., 2022
CBS is required for oocyte quality by ensuring proper spindle assembly. During oocyte meiotic maturation, CBS ensures spindle assembly by participating in the acetylation of α‐tubulin to stabilize microtubules. Kinetochores remain attached by spindle microtubules. SAC is removed from the kinetochores and then the chromosomes can be separated correctly.
Yan Cao, Xinyu Zhu, Panpan Zhen, Ying Tian, Dengyu Ji, Ke Xue, Wenjing Yan, Jiayin Chai, Huirong Liu, Wen Wang   +9 more
wiley   +1 more source

Quality control of eggs using multivariate analysis of micro-Raman spectroscopy [PDF]

arXiv, 2023
Considering the pivotal role of eggs in the food industry and their nutritional significance, this study employed micro-Raman spectroscopy of eggs, examining both shells and yolks to assess the quality and freshness of eggs. Raman spectra were collected at different temperatures and time intervals to investigate temperature and time effects ...
arxiv  

Confinement by Liquid‐Liquid Interface Replicates In Vivo Neutrophil Deformations and Elicits Bleb‐Based Migration

Advanced Science, EarlyView.
Leukocytes sense mechanical cues provided by surrounding cells to regulate motility. Replicating the confining pressures applied by soft, elastic tissues in vitro is challenging. Here, the use of liquid‐liquid interfaces is introduced to model forces exerted by surrounding cells. Confining pressures are tunable by controlling interfacial curvature, and
Jonathan H. Schrope, Adam Horn, Kaitlyn Lazorchak, Clyde W. Tinnen, Jack J Stevens, Mehtab Farooqui, Tanner Robertson, Jiayi Li, David Bennin, Terry Juang, Adeel Ahmed, Chao Li, Anna Huttenlocher, David J Beebe   +13 more
wiley   +1 more source

Nuclear Translocation of S100A9 Triggers Senescence of Human Amnion Fibroblasts by De‐Repressing LINE1 Via Heterochromatin Erosion at Parturition

Advanced Science, EarlyView.
This study shows that the classical secretory protein S100 calcium‐binding protein A9 (S100A9) can translocate to the nucleus upon de‐phosphorylation at Thr 113 in human amnion fibroblasts at parturition, where S100A9 induces heterochromatin erosion through segregation of the heterochromatin maintenance protein, resulting inLong Interspersed Nuclear ...
Fan Zhang, Meng‐Die Li, Fan Pan, Wen‐Jia Lei, Yang Xi, Li‐Jun Ling, Leslie Myatt, Kang Sun, Wang‐Sheng Wang   +8 more
wiley   +1 more source

Free iron accumulation and oxidative stress burden induce ferroptotic atrophy of chicken yolk sac during the late embryogenesis

Animal Research and One Health
The aim of this study was to investigate the mechanism of iron homeostasis and the ferroptosis pathway for yolk sac atrophy during late embryogenesis. To study the mechanism of yolk sac atrophy, 100 eggs were used. Further, 500 eggs were randomly divided
Huichao Liu, Zehe Song, Xi He, Haihan Zhang   +3 more
doaj   +1 more source

Wnt Inhibition Safeguards Porcine Embryonic Stem Cells From the Acquisition of Extraembryonic Endoderm Cell Fates

Advanced Science, EarlyView.
The study reports that Wnt inhibitors safeguard porcine embryonic stem cells (ESCs) from acquiring the extraembryonic endoderm (XEN) lineage, and further develop an efficient strategy to derive XEN cells from ESCs. The XEN cells from ESCs exhibit similar transcriptome and chromatin accessibility features to XEN cells from embryos and contribute to ...
Hanning Wang, Liang Zhong, Zhuangfei Wang, Jinzhu Xiang, Duanqing Pei   +4 more
wiley   +1 more source

On a generalized Auslander-Reiten conjecture [PDF]

arXiv, 2022
It is well-known that the generalized Auslander-Reiten condition (GARC) and the symmetric Auslander condition (SAC) are equivalent, and (GARC) implies that the Auslander-Reiten condition (ARC). In this paper we explore (SAC) along with the several canonical change of rings $R \to S$. First, we prove the equivalence of (SAC) for $R$ and $R/xR$, where $x$
arxiv  

Yolk sac fatty acid composition, yolk absorption, embryo development, and chick quality during incubation in eggs from young and old broiler breeders.

Poultry Science, 2014
The objective of the present study was to examine the changes in yolk and yolk sac fatty acid composition and also to investigate egg content, yolk absorption, embryo development during incubation, and chick quality at hatch in eggs from 36- and 52-wk ...
U. Sahan, A. İpek, A. Sozcu
semanticscholar   +1 more source

Zinc‐Doping‐Induced Electronic States Modulation of Molybdenum Carbide: Expediting Rate‐Determining Steps of Sulfur Conversion in Lithium‐Sulfur Batteries

Advanced Science, EarlyView.
Zn‐doped molybdenum carbide microflowers (Zn‐Mo2C) are exploited as a sulfur host for Li–S batteries. Zn doping elevates the d‐band center on Mo, enhancing LiPSs anchoring, weakening S─S/Li─S bonds, and reducing Li2S2→Li2S conversion energy barrier from 0.52 to 0.05 eV.
Bin Qin, Yanmei Li, Qun Wang, Si Zhang, Jinglin Zhang, Bin Wang, Peijia Wang, Yuhan Chen, Weiqi Yao, Fang Wang   +9 more
wiley   +1 more source