Results 111 to 120 of about 17,199 (227)
Leveraging Macrophage Metabolic Reprogramming for Enhanced Anti‐Tumor Immunity
Tumor‐associated macrophages (TAMs) are key regulators of the tumor microenvironment (TME), with their metabolic states playing a critical role in tumor progression or regression. This review summarizes current understanding of TAM metabolic plasticity alongside cutting‐edge bioengineering innovations, outlining a roadmap for transforming the ...
Zhiyun Liu +8 more
wiley +1 more source
Hepatocellular carcinoma (HCC)‐derived extracellular vesicles (EVs) enrich the metabolic enzyme ATP‐citrate lyase (ACLY). EV‐transferred ACLY enhances palmitate biosynthesis, increases the S‐palmitoylation and stability of multiple immune checkpoint proteins, augments the cellular immunosuppressive activity, and ultimately accelerates the malignant ...
Zhijun Liu +11 more
wiley +1 more source
The Human Yolk Sac and Yolk Sac Tumors [PDF]
openaire +1 more source
Malignant Ovarian Germ Cell Tumor—Survival and Reproductive Outcomes and Patterns of Relapse
BLURB FOR ETOC: Patients presenting with advanced MOGCT can be offered fertility‐sparing surgery after neoadjuvant chemotherapy with no detriment in oncological outcome. ABSTRACT Background Malignant ovarian germ cell tumors [MOGCT] are rare cancers affecting young women and often present in advanced stages.
Sayak Dey +24 more
wiley +1 more source
ABSTRACT Background Testicular cancer represents the most common solid tumor in young adult males and is associated with excellent long‐term survival outcomes. Aim The aim of this study is to evaluate clinical and pathological characteristics, treatment strategies, and survival outcomes of a large Romanian institutional cohort.
Emanuiela Florentina Rohozneanu +2 more
wiley +1 more source
Infantile Testicular Tumor (Yolk Sac Tumor) : A Case Report [PDF]
A 5-month-old-male was brought to our hospital in April 2004 with left scrotal swelling. His serum alpha-fetoprotein AFP and human chorionic gonadotropin-β levels were 6, 862.9 and < 0.1 ng/ml, respectively.
小宮, 敦 +12 more
core
Bilateral lung metastases unveils an asymptomatic sacrococcygeal yolk sac tumor
Sacrococcygeal yolk sac tumor is an uncommon pediatric neoplasm. It usually presents with intra-abdominal or gluteal pain and mass. At later stage, it disseminates to regional nodes and distant organs.
Krishnendu Mondal, Rupali Mandal
core +1 more source
Morphological Analysis of Yolk Sac Tumor.
Morphological analysis of imprint histology and cytology was performed in 7 patients with yolk sac tumor (YST). As a result, histological figures of YST were classified into 4 patterns. Endodermal sinus pattern was most frequently identified, followed by polyvesicular vitelline pattern.
openaire +3 more sources
Abstract Zebrafish embryos provide a rapid, low‐cost in vivo platform to profile the developmental, neurotoxic, and immunomodulatory effects of engineered nano(bio)materials within a single vertebrate system. This article presents a modular workflow that integrates standardized fish embryo acute toxicity (FET) testing, chemically assisted ...
Cinzia Bragato +8 more
wiley +1 more source
TREM2hi microglia and macrophages exert distinct roles in neurological diseases. Enhancing TREM2 signalling supports pathological protein or debris clearance and mitigates inflammation in Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, demyelination disorders and stroke, whereas blocking TREM2 may alleviate tauopathy and ...
Zhe Kong +3 more
wiley +1 more source

