Results 111 to 120 of about 13,535,371 (355)
Young People and Digital Intimacies. What is the evidence and what does it mean? Where next? [PDF]
, 2019 The digital age makes new forms of connection possible, enabling ‘digital intimacies’ including the many practices of communicating, producing and sharing intimate content (‘sexting’; selfies; making, viewing and circulating sexual content; using hook-up
Attwood, Feona +2 more
core
Prevalence of Prediabetes Among Adolescents and Young Adults in the United States, 2005-2016.
JAMA pediatrics, 2019 Importance Individuals with prediabetes are at increased risk of developing type 2 diabetes, chronic kidney disease, and cardiovascular disease. The incidence and prevalence of type 2 diabetes in the US adolescent population have increased in the last ...
L. Andes +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Glucose-6-phosphate dehydrogenase deficiency with coinherited Gaucher disease: A rare association
Indian Journal of Pathology and MicrobiologyAnemia coexisting with Gaucher disease (GD) is often associated with non-hemolytic processes. Few cases of GD with autoimmune hemolytic anemia have been reported. However, literature on GD with concomitant nonimmune hemolytic anemia is scarce. A 1-year 6-
Nupur Parakh +4 more
doaj +1 more source
WP7 Regional/local Case Studies [PDF]
, 2018 This report provides an in depth and transversal analysis of the policy Developing the Young Workforce (DYW) in Glasgow City Region and Aberdeen City and Aberdeenshrie Region.
Capsada-Munsech, Queralt
core
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Recommendations for Using Online Social Networking Technologies to Reduce Inaccurate Online Health Information [PDF]
, 2011 This short report highlights patients' increasing use of the Internet and online social networking technologies to seek health information, and the consequences of gaining information from sites with biased or inaccurate health information. Reflecting on
Young, SD
core +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source