Results 81 to 90 of about 275,905 (218)

A rare case of isolated left main coronary artery disease in a young patient

Heart India
Isolated stenosis of the left coronary artery is extremely rare. Studies have shown a 2%–10% incidence of acute myocardial infarction in patients aged 45 years or younger. Stable angina and multivessel disease are uncommon in the young.
Ishan Gohil, Anand Ratra, Utkarsh Sanghavi, Jignesh Kothari   +3 more
doaj   +1 more source

How young is young in 2010? Defining the young woman

, 2010
Dédier un livre au cancer du sein de la femme jeune nécessite, avant tout débat, de définir la notion même de jeunesse. Qu’ entend-on par femme jeune ? Cette appellation “femme jeune, jeune femme” n’ a pas de définition univoque… Dans le numéro de septembre 2010 de Breast Cancer Research and Treatment, Marina Pollan souligne d’ emblée, dans son ...
Lesur, A., Escoute, M.
openaire   +2 more sources

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Short-term outcome of total hip arthroplasty using dual-mobility cups for secondary osteoarthritis hip in the Indian population

Journal of Orthopaedic Diseases and Traumatology, 2019
Purpose: The aim was to evaluate the functional outcome and dislocation rate at a minimum of 1-year follow-up following total hip replacement (THR) using Stryker modular dual mobility (MDM) X3 Mobile Bearing Hip System.
Sudeep Kumar, Anup Kumar, Ravi Kumar
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Dimensions of Memory in Elderly Compared with Non-Elderly [PDF]

روانشناسی پیری, 2019
Growing old causes significant effects on cognitive and metacognitive processes and increases the likelihood of cognitive failure. The present study aimed to investigate various dimensions of memory in the elderly and compare it with non-elderly.
Kamran Yazdanbakhsh, Mohammad Jashenpour, Amir Sanjabi, Akram Abbariki   +3 more
doaj  

Young and thriving is okay; young and not thriving is not [PDF]

The Journal of Thoracic and Cardiovascular Surgery, 2017
Timothy J, Pirolli, Robert D B, Jaquiss
openaire   +2 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Urothelial neoplasm in a 19‐year‐old male patient with urine discoloration, negative lab, and imaging workup: Should we investigate the findings or the symptom?

Clinical Case Reports, 2019
Key Clinical Message With few cases of PUNLMPs in young adults being reported in the literature, we hope to raise clinical awareness of prompt and effective diagnosis, while maintaining a high index of suspicion among health professionals.
Evangelos N. Symeonidis, Asterios Symeonidis, Chrysovalantis Gkekas, Christos Georgiadis, Apostolos Malioris, Michail Papathanasiou   +5 more
doaj   +1 more source