Results 111 to 120 of about 1,316,712 (317)

Models of Multi-agency Services for Transition to Adult Services for Disabled Young People and those with Complex Health Needs: Impact and Costs. Report to the Department of Health [PDF]

, 2010
The research aimed to provide evidence of what works in developing and implementing multi-agency co-ordinated transition services for disabled young people and those with complex health needs and their families: ?
Franklin, Anita, Moran, Nicola, Sloper, Patricia, Clarke, Susan, Beecham, Jennifer, Cusworth, Linda   +5 more
core  

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Hip and Pelvis Movement Patterns in Patients With Femoroacetabular Impingement Syndrome Differ From Controls and Change After Hip Arthroscopy During a Step-Down Pivot-Turn Task

Orthopaedic Journal of Sports Medicine
Background: Alterations in hip kinematics during functional tasks occur in positions that cause anterior impingement in patients with femoroacetabular impingement (FAI) syndrome.
Thomas D. Alter MD, Daniel M. Wichman BS, Thomas W. Fenn BS, Derrick M. Knapik MD, Alejandro Espinoza Orias PhD, Shane J. Nho MS, MD, Philip Malloy PT, PhD   +6 more
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Socioeconomic position in childhood and adult cardiovascular risk factors, vascular structure, and function: cardiovascular risk in Young Finns study

, 2005
Objective: To examine the association of childhood socioeconomic position (SEP) with adult cardiovascular risk factors, vascular structure, and vascular function in a contemporary population of young adults. Design: Population based prospective cohort
Keltikangas-Järvinen, L., Kivimäki, M, Ferrie, J E, Keltikangas-Järvinen, L, Raitakari, O.T., Raitakari, O T, Elovainio, M., Viikari, J.S.A., Vahtera, J, Elovainio, M, Juonala, M., Viikari, J S A, Vahtera, J., Leino, M, Pulkki-Råback, L., Smith, Davey G, Davey Smith, G., Ferrie, J.E., Juonala, M, Leino, M., Pulkki-Råback, L, Kivimäki, M.   +21 more
core  

Development and implementation of a website assessment tool to evaluate policies and resources for sexual assault and alcohol use on US college campuses

BMC Global and Public Health
Background Sexual assault on college campuses is a major public health concern. Over half of incidents of sexual violence on college campuses occur in the context of victim or perpetrator alcohol use.
Elizabeth A. Walker, Regina Futcher, Naomi Segel, Nandana Menon, Julia Vroman, Alyssa E. Gribov, Kayla Ortiz, Robert W. S. Coulter, Christina F. Mair, Elizabeth Miller, Rachel E. Gartner   +10 more
doaj   +1 more source

Predictors of poor outcomes in juvenile dermatomyositis: what do we know? A narrative review

Reumatismo
Objective. Juvenile dermatomyositis (JDM) is a rare chronic systemic inflammatory disorder with a highly variable clinical course. It is important to identify the patients at risk of developing more severe disease.
A. Martins, S. Ganhão, F. Aguiar, M. Rodrigues, I. Brito   +4 more
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

CONSUMER DECISION-MAKING STYLES AND YOUNG-ADULT CONSUMERS: AN INDIAN EXPLORATION [PDF]

The economy of India is on a growth spree since the last two decades. This growth has increased the shopping options available to the consumers. The present study has tried to ascertain the decision-making styles of young-adult consumers so as to provide
Anubhav Anand MISHRA
core  

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source