Results 41 to 50 of about 946,124 (262)

Bone and Soft Tissue Neoplasms in Infants Versus Older Children: A Report From the Cancer in Young People in Canada Program

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Infant bone and soft tissue neoplasms present distinct clinical challenges and lack large‐scale data to inform treatment decisions. This study aims to characterize bone and soft tissue neoplasms in infants in Canada and to compare their outcomes with those of older pediatric patients.
Samuel Sassine, Hallie Coltin, Maria Kondyli, Monia Marzouki, Nicolas Prud'homme, Nida Usmani, Rebecca J. Deyell, Lesleigh Abbott, Tony H. Truong, Sapna Oberoi, Ketan Kulkarni, Josée Brossard, Lynette Bowes, Paul Gibson, Sarah McKillop, Roona Sinha, Lillian Sung, Catherine Vezina, Laura Wheaton, Alexandra P. Zorzi, Marie‐Claude Pelland‐Marcotte, Thai Hoa Tran   +21 more
wiley   +1 more source

Safe at home? Factors influencing the safety strategies used by people with intellectual disability

Scandinavian Journal of Disability Research, 2013
Little is known about how people with intellectual disability understand personal safety, or what strategies they call upon when they do not feel safe in their homes. In this participatory research, 20 people with intellectual disability talked about the
Sally Robinson
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Exploring How Children and Young People With Sickle Cell Disease and Their Families Want to be Involved in Research: A Qualitative Study

Health Expectations
Background There is growing emphasis on the importance of Patient and Public Involvement and Engagement in research to ensure it addresses the needs of the target population.
Jane Chudleigh, Addassa Follett, Ethan Mcfarlane‐Griffith, Derick Abuo, Josh, Imani, Pru Holder   +6 more
doaj   +1 more source

What types of objective measures have been used to assess core ADHD symptoms in children and young people in naturalistic settings? A scoping review

BMJ Open
Objectives We described the range and types of objective measures of attention-deficit/hyperactivity disorder (ADHD) in children and young people (CYP) reported in research that can be applied in naturalistic settings.Design Scoping review using best ...
Obioha C Ukoumunne, Darren Moore, Jo Thompson Coon, Rebecca Gudka, Charlotte Rose Kelman, Eleanor F Bryant, Abigail Russell   +6 more
doaj   +1 more source

“Could we have predicted this?” The association of a future mental health need in young people with a non‐specific complaint and frequent emergency department visits

Journal of the American College of Emergency Physicians Open, 2021
Objective Mental health emergencies among young people are increasing. There is growing pressure for emergency departments to screen patients for mental health needs even when it is not their chief complaint.
Andrea Fang, Melissa Hersh, Natalia Birgisson, Olga Saynina, Nancy E Wang   +4 more
doaj   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

FEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page, Rachel J. Hunt, Lauren J. Albee, Daniel Berwick, Alison Snape   +4 more
wiley   +1 more source

Co-producing data-intensive research with an underserved group: a case study and evaluation identifying pathways to impact

International Journal of Population Data Science
Introduction Co-production of research, where researchers and experts by experience work as equal partners throughout a research project, can improve the quality, relevance, implementation and impact of research.
Sarah McKenna, Ash Salem, Esla Ibrahim, Rhianna Brown, Martha McCallin, Brenda Kilpatrick, Jo Irvine, Lee Kane, Elizabeth Nelson, Aideen Maguire   +9 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source