Results 81 to 90 of about 158,628 (345)

Age‐Related Changes in Myeloid Cells and Their Impact on Subcutaneous Melanoma Growth in Mice

Aging and Cancer, EarlyView.
Our findings reveal that age‐related changes in subcutaneous melanoma growth and immunotherapy response are context‐dependent. In models where tumor growth and treatment resistance increase with age, this effect is partly driven by enhanced immunosuppression from myeloperoxidase‐active Gr‐1⁺ myeloid cells.
Kaitlyn M. Landreth, Dylan D. Thomas, Remi Nohoesu, Angisha Basnet, F. Heath Damron, Mary Garland‐Kledzik, Emel Sen Kilic, Tracy W. Liu   +7 more
wiley   +1 more source

Outflow and accretion detections in the young stellar object IRAS 04579+4703

, 2012
We present Submillimeter Array observations of the young stellar object IRAS 04579+4703 in the 1.3 mm continuum and in the 12CO(2-1), 13CO(2-1) and C18O(2-1) lines. The 1.3 mm continuum image reveals a flattened structure with a mass of 13 Msun. The 12CO(
André, Belloche, Beltrán, Beuther, Cesaroni, Chen, Dickman, Draine, Furuya, Garden, Ishii, Jiang, Jin-Long Xu, Jun-Jie Wang, Keto, Lis, Migenes, Molinari, Molinari, Molinari, Myers, Palla, Patel, Qin, Qin, Reid, Sewilo, Sheng-Li Qin, Shepherd, Shu, Sánchez-Monge, Testi, Varricatt, Weintroub, Wouterloot, Wu, Xu, Yamashita, Zhang, Zinnecker   +39 more
core   +1 more source

Large-scale Effect of an Accretion Burst in the High-Mass Young Stellar Object G358.93-0.03-MM1

The Astronomical Journal
The high-mass young stellar object G358.93-0.03-MM1 underwent a rapid accretion burst event from 2019 January to June, resulting in flares observed in most class II methanol maser transitions starting in mid-January.
Dan Miao, Xi Chen, Olga S. Bayandina, Andrej M. Sobolev, Wan-jun Li, Koichiro Sugiyama   +5 more
doaj   +1 more source

Cystic Ovarian Teratoma: Clinical and Radiographic Insights Into Chronic Pelvic Pain

Aging and Cancer, EarlyView.
An incidental benign mature cystic ovarian teratoma on imaging and discuss common imaging modalities. ABSTRACT In this case report, we present the clinical course of an 88‐year‐old woman with chronic pelvic pain attributed to an incidental benign mature cystic ovarian teratoma on imaging and discuss common imaging modalities and discussions with ...
Hashim U. Ali, Fahad H. Malik, Mohammad M. Zia, Ashar Ahmed, Mahfujul Z. Haque, Masood Siddiqui   +5 more
wiley   +1 more source

Binary Black Hole Mergers and Intermediate-mass Black Holes in Dense Star Clusters with Collisional Runaways

The Astronomical Journal
Intermediate-mass black holes (IMBHs) are believed to be the missing link between the supermassive black holes (BHs) found at the centers of massive galaxies and BHs formed through stellar core collapse. One of the proposed mechanisms for their formation
Rujuta A. Purohit, Giacomo Fragione, Frederic A. Rasio, Grayson C. Petter, Ryan C. Hickox   +4 more
doaj   +1 more source

RNO 54: A Previously Unappreciated FU Ori Star

The Astrophysical Journal Letters, 2023
We present evidence in support of the hypothesis that the young stellar object RNO 54 is a mature-stage FU Ori type source. The star was first cataloged as a “red nebulous object” in the 1980s but appears to have undergone its outburst prior to the 1890s.
Lynne A. Hillenbrand, Adolfo Carvalho, Jan van Roestel, Kishalay De   +3 more
doaj   +1 more source

Protein Tyrosine Phosphatase 4A1 (PTP4A1) Regulates Early Events in Colorectal Cancer Intraperitoneal Dissemination in the Aged Male Host

Aging and Cancer, EarlyView.
Colorectal cancer (CRC) mortality is highest in aged males. Pre‐clinical data comparing CRC i.p. metastasis in cohorts of young and aged, male and female mice support these finding. Bottom‐up proteomics of peritoneal mesothelial cells identified PTP4A1 as highly expressed in aged males and a role for PTP4A1 in heterotypic cell:cell adhesion was ...
Zhikun Wang, Yueying Liu, Jing Yang, Tyvette S. Hilliard, Reihaneh Safavi‐Sohi, Daniel D. Hu, Elizabeth I. Harper, Gena Dominique, Wanrui Wang, Jeffrey Johnson, Marwa Asem, William Milosevich, Julia Florek Carlson, Yunpeng Bai, Jinmin Miao, Zhong‐Yin Zhang, Matthew M. Champion, M. Sharon Stack   +17 more
wiley   +1 more source

Evolution of the Jet-Feedback Mechanism (JFM)

, 2017
I list eight types of astrophysical objects where jets, and more particularly the jet feedback mechanism (JFM), might operate, and discuss cases where an object evolves from one type to another while the JFM continues to operate. In four of these classes
Soker, Noam
core   +1 more source

Cooling Process of the High-mass Young Stellar Object G24.33+0.14 Following an Accretion Burst

The Astronomical Journal
The high-mass young stellar object G24.33+0.14 (G24), has recently been observed to undergo an accretion burst since 2019 September, lasting approximately two years.
Xiaoyun Xu, Xi Chen, Yang Yang
doaj   +1 more source

Trends and Disparities in Lung Cancer and Respiratory Failure Mortality in the United States: A 24‐Year Retrospective Study

Aging and Cancer, EarlyView.
Mortality from lung cancer and respiratory failure in US adults declined until 2010 but increased thereafter, with notable disparities by sex, race, region, and urbanicity. This 24‐year analysis highlights rising post‐2010 mortality in women, non‐Hispanic Whites, and urban areas, underscoring the need for targeted public health interventions.
Sardar M. I. Khan, Muneeb Khawar, Abdul Qadeer, Aqsa Komel, Azka Aisha, Arshia Batool, Ayesha Fatima, Javed Iqbal, Asraf Hussain, Anisha Manzoor, Muhammad Waqas   +10 more
wiley   +1 more source