Results 81 to 90 of about 80,201 (344)
We present a combined Hubble Space Telescope (HST) and JWST 0.2–to–5 μ m analysis of the spectral energy distributions (SED) of emerging young star clusters (eYSCs) in four nearby galaxies from the Feedback in Emerging Extrgalactic Star Clusters survey ...
Alex Pedrini +25 more
doaj +1 more source
Molecular Outflows from Young Stellar Objects
30 pages, 6 figures. To appear in Protostars & Planets IV, eds. V. Mannings, A. Boss, S. Russell (Tucson: The University of Arizona Press)
Richer, John +4 more
openaire +2 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
We explore the physical environment of the Galactic mid-infrared (MIR) bubble [HKS2019] E71 (hereafter E71) through a multiwavelength approach. E71 is located at the edge of a filamentary structure, as traced in Herschel images (250–500 μ m), Herschel ...
Aayushi Verma +10 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Probing discs around massive young stellar objects with CO first overtone emission
We present high resolution (R~50,000) spectroastrometry over the CO 1st overtone bandhead of a sample of seven intermediate/massive young stellar objects.
de Wit, W. J. +5 more
core +1 more source
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
We analyzed optical/near-IR Large Binocular Telescope spectra of 16 sources alerted by Gaia between 2021 and 2024 due to significant photometric variability.
Teresa Giannini +15 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source

