Results 81 to 90 of about 80,201 (344)

The Near Infrared Spectral Energy Distribution of Young Star Clusters in the FEAST Galaxies: Missing Ingredients at 1–5 μm

open access: yesThe Astrophysical Journal
We present a combined Hubble Space Telescope (HST) and JWST 0.2–to–5 μ m analysis of the spectral energy distributions (SED) of emerging young star clusters (eYSCs) in four nearby galaxies from the Feedback in Emerging Extrgalactic Star Clusters survey ...
Alex Pedrini   +25 more
doaj   +1 more source

Molecular Outflows from Young Stellar Objects

open access: yes, 1999
30 pages, 6 figures. To appear in Protostars & Planets IV, eds. V. Mannings, A. Boss, S. Russell (Tucson: The University of Arizona Press)
Richer, John   +4 more
openaire   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Unraveling the Feedback-regulated Star Formation Activities around the Expanding Galactic Mid-infrared Bubble [HKS2019] E71

open access: yesThe Astrophysical Journal
We explore the physical environment of the Galactic mid-infrared (MIR) bubble [HKS2019] E71 (hereafter E71) through a multiwavelength approach. E71 is located at the edge of a filamentary structure, as traced in Herschel images (250–500 μ m), Herschel ...
Aayushi Verma   +10 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Probing discs around massive young stellar objects with CO first overtone emission

open access: yes, 2010
We present high resolution (R~50,000) spectroastrometry over the CO 1st overtone bandhead of a sample of seven intermediate/massive young stellar objects.
de Wit, W. J.   +5 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Spectroscopic Follow-up of Gaia Alerted Young Stellar Object Variables: The Large Binocular Telescope View

open access: yesThe Astrophysical Journal
We analyzed optical/near-IR Large Binocular Telescope spectra of 16 sources alerted by Gaia between 2021 and 2024 due to significant photometric variability.
Teresa Giannini   +15 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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