Results 121 to 130 of about 6,184 (301)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Magnetically Controlled Accretion Flows onto Young Stellar Objects [PDF]

, 2011
Accretion from disks onto young stars is thought to follow magnetic field lines from the inner disk edge to the stellar surface. The accretion flow thus depends on the geometry of the magnetic field.
Gregory, Scott G.; id_orcid, Adams, Fred C., Fred C. Adams, Scott G. Gregory, G. Gregory, Scott, Gregory, Scott G., C. Adams, Fred   +6 more
core   +1 more source

The Disk Orientations of Perseus Protostellar Multiples at ∼8 au Resolution

The Astrophysical Journal
We present a statistical characterization of circumstellar disk orientations toward 12 protostellar multiple systems in the Perseus molecular cloud using the Atacama Large Millimeter/submillimeter Array at Band 6 (1.3 mm) with a resolution of ∼25 mas (∼8
Nickalas K. Reynolds, John J. Tobin, Patrick D. Sheehan, Sarah I. Sadavoy, Leslie W. Looney, Kaitlin M. Kratter, Zhi-Yun Li, Dominique M. Segura-Cox, Nathan A. Kaib   +8 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Externally Illuminated Young Stellar Objects in the Orion Nebula [PDF]

, 2008
. The circumstellar material surrounding most low-mass young stars in the Orion Nebula Cluster is rendered visible by the ionizing radiation of the hot Trapezium stars and the background light of M42.
John Bally
core  

JWST Mid-infrared Spectroscopy Resolves Gas, Dust, and Ice in Young Stellar Objects in the Large Magellanic Cloud

The Astrophysical Journal
In this work, we present spectra of 11 young stellar objects (YSOs) taken with the Mid-Infrared Instrument / Medium Resolution Spectroscopy (MRS) instrument on board the James Webb Space Telescope (JWST).
Omnarayani Nayak, Alec S. Hirschauer, Patrick J. Kavanagh, Margaret Meixner, Laurie Chu, Nolan Habel, Olivia C. Jones, Laura Lenkić, Conor Nally, Megan Reiter, Massimo Robberto, B. A. Sargent   +11 more
doaj   +1 more source

Backlighting young stellar objects in the Central Molecular Zone

Astronomy & Astrophysics
Context. The Central Molecular Zone (CMZ) of the Milky Way contains a substantial reservoir of dense molecular gas, where numerous young stellar objects (YSOs) and dense cloud cores have been identified, offering valuable opportunities to investigate ...
Kang Yewon, An Deokkeun, Han Jiwon, Han Sang-Il, Pyo Dayoung, Adwin Boogert A. C., Kim Kee-Tae, Byun Do-Young   +7 more
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Young Stellar Objects in Lynds 1641: a submillimetre continuum study. [PDF]

, 1997
International audienceWe present observations of the 350\ensuremathμm-1.3mm continuum emission of a sample of ten Class I young stellar objects in the Lynds 1641 (L1641) molecular cloud.
Zavagno, Annie, Saraceno, P., Tommasi, E., Griffin, M., Molinari, S.   +4 more
core