Results 161 to 170 of about 170,516 (335)

Illuminating New Frontiers: Exploring the Photosensitizing Potential of Passiflora Species in Combating Methicillin‐Resistant Staphylococcus aureus (MRSA) and Their Infection in Senescent Mice

open access: yesAdvanced Biology, EarlyView.
This study investigates the photosensitizing potential of Passiflora cincinnata in Antimicrobial Photodynamic Therapy (aPDT) against skin infection caused by Methicillin‐resistant Staphylococcus aureus (MRSA) in a senescent murine model. The P. cincinnata exhibits antimicrobial activity, with reduced bacterial load, lower leukocyte infiltration, and ...
Caroline Vieira Gonçalves   +14 more
wiley   +1 more source

Characterizing the Multiple Protostellar System VLA 1623-2417 with JWST, ALMA, and VLA: Outflow Origins, Dust Growth, and an Unsettled Disk

open access: yesThe Astrophysical Journal
Utilizing the James Webb Space Telescope (JWST), the Atacama Large Millimeter/submillimeter Array (ALMA), and the Very Large Array (VLA), we present high angular resolution (0 $\mathop{.}\limits^{^{\prime\prime} }$ 06–0 $\mathop{.}\limits^{^{\prime\prime}
Isaac C. Radley   +18 more
doaj   +1 more source

Primary Human Tissue Models for Metabolic Dysfunction‐Associated Liver Disease ‐ toward Streamlining Drug Discovery with Patient‐Derived Assays

open access: yesAdvanced Biology, EarlyView.
The review provides a critical up‐to‐date overview of the current landscape of human in vitro models for fatty liver disease, including spheroids, organoids, organ‐on‐a‐chip systems, bioprinted liver constructs and precision‐cut liver slices. Their utility for faithfully modeling different stages of MASLD and MASH are evaluated and their compatibility ...
Sonia Youhanna   +6 more
wiley   +1 more source

PROJECT-J: JWST Observations of HH46 IRS and Its Outflow. Overview and First Results

open access: yesThe Astrophysical Journal
We present the first results of the JWST program PROJECT-J (PROtostellar JEts Cradle Tested with JWST), designed to study the Class I source HH46 IRS and its outflow through NIRSpec and MIRI spectroscopy (1.66–28 μ m). The data provide line images (∼6.″6
Brunella Nisini   +25 more
doaj   +1 more source

A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study

open access: yesAdvanced Biology, EarlyView.
Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers   +10 more
wiley   +1 more source

Osteocytes under Mechanical Loading Regulate PC‐3 Cancer Cell–Mineral Interactions during Early‐Stage Metastasis to Bone

open access: yesAdvanced Biology, EarlyView.
In this study, Seaman et al. develop a co‐culture assay to examine interactions between prostate cancer cells and mineralized osteoblasts in a microfluidic platform. The authors collect conditioned media from static or flow‐stimulated osteocytes and demonstrate that mechanical loading of osteocytes regulates the growth of prostate cancer cells and ...
Kimberly Seaman   +5 more
wiley   +1 more source

Young Stellar Object Jets Magnetocentrifugally Driven by Reconnecting Atmospheric Avalanche Accretion Streams above Inner Circumstellar Disks

open access: yesThe Astrophysical Journal
Fast, collimated jets are ubiquitous features of young stellar objects. They are generally thought to be powered by disk accretion, but the details are debated.
Yisheng Tu   +4 more
doaj   +1 more source

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