Results 171 to 180 of about 2,948,019 (406)

Western Diet Inhibits FUT7‐Mediated Treg Intestinal Homing to Disrupt the Homeostasis of Intestinal Epithelial Cells in Crohn's Disease

Advanced Science, EarlyView.
In this study, we constructed a nanoparticle that was CD4 antibody‐mediated targeted, Fut7‐expressing plasmid‐loaded cationic liposome, namely CD4‐LDP‐Fut7. Upregulation of Fut7 expression in Tregs by using CD4‐LDP‐Fut7 can increase Treg homing to the intestine, thereby facilitating repair of the intestinal epithelial barrier and inhibiting ...
Qian Zhou, Xianfei Wang, Teng Ben, Chunping Zhu, Xinlong Lin, Yinmu Li, Xinyue Zhang, Yeling Chen, Yuchen Xuan, Huaiwen Chen, Ke Liu, Fang Wu, Yuexin Ren, Gao Tan   +13 more
wiley   +1 more source

A systematic survey of type I secretion systems and their substrate proteins in Salmonella

Virulence
Type I secretion systems (T1SSs) and the substrates have not been investigated extensively in Salmonella, despite their potential significance. In this research, we screened the comprehensive list of Salmonella T1SSs, observed their evolution and ...
Mingyang Yu, Yating Chen, Xin Cao, Zefan Chen, Shichao Su, Jiamin Wu, Leting Sun, Qiqi Lu, Chenxia Zhang, Zhixuan Deng, Jialin Li, Jingchao Zhong, Yejun Wang   +12 more
doaj   +1 more source

Even Better than the Real Thing [PDF]

, 2016
In an era where the youth were obsessed with an appearance of success and being hip, when Coke finally altered its New Coke brand identity to appeal to the youth, they still could not make the youth accept New Coke. In the end when Coke had the chance to
Moran, Nicholas
core   +1 more source

Wedelolactone, a Novel TLR2 Agonist, Promotes Neutrophil Differentiation and Ameliorates Neutropenia: A Multi‐Omics Approach to Unravel the Mechanism

Advanced Science, EarlyView.
Wedelolactone (WED), a natural TLR2 agonist, promotes neutrophil differentiation and enhances bactericidal function, offering a potential therapeutic strategy for neutropenia. Using a multi‐omics approach, this study reveals that WED activates the TLR2/MEK/ERK pathway, upregulating key transcription factors (PU.1, CEBPβ) to drive neutrophil development.
Long Wang, Zhichao Li, Tianci Hu, Qinyao Li, Linwei Zhang, Xinyue Mei, Xiao Qi, Sheng Liu, Weijie Kong, Jiesi Luo, Anguo Wu, Feihong Huang, Sirui Li, Shuang Dai, Chunxiang Zhang, Rong Li, Jianming Wu   +16 more
wiley   +1 more source

Lost youth [PDF]

Journal of the Intensive Care Society, 2017
, Wood, , Trees
openaire   +2 more sources

Cinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU

Advanced Science, EarlyView.
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen, Yingqi Xu, Zhaoping Xiong, Hongliang Wang, Xin Wang, Yue Kang, Zhonglin Wang, Xiaoyan Zeng, Yahui Liu, Yehuan Zheng, Wei Chen, Mengzhe Li, Zhenyue Hu, Chi Xu, Yue Wu, Yawen Wang, Zuyi Yuan, Shuai Yuan, Huadong Liu, Steve Matthews, Nan Qiao, Yan Li, Bing Liu   +22 more
wiley   +1 more source

Advancing Equity through Effective Youth Engagement in Public Health to Operationalize Racism as a Public Health Crisis: The Flint Public Health Youth Academy Model

Youth
Background: The underrepresentation of BIPOC youth in the fields of public health, medicine, and research may be a factor contributing to the disproportionate rates of health disparities in BIPOC communities. In 2004, the Sullivan Commission on Diversity
Kent D. Key, Kayla Shannon, Everett Graham, Cruz Duhart, Tomás Tello, Cole Mays, Christian Mays, Tyshae Brady, Jasmine Hall, Kahlil Calvin, Courtney Blanchard, Vanessa de Danzine, Sarah Bailey   +12 more
doaj   +1 more source

Youth-to-Youth Engagement

International Journal of Recent Technology and Engineering, 2019
Youth-to-youth engagement develops as well as enhances sense of belonging, autonomy and power control, competence, motivation and decision-making skills. Millennial youth are self-learned generation; thus, peer influence is vital. Based on these premises, GENIUS Remaja programmes are created ‘with youths’ rather than ‘for youth’.
openaire   +1 more source

Emotional reactivity and regulation in anxious and nonanxious youth: a cell‐phone ecological momentary assessment study

, 2011
Patricia Z. Tan, Erika E. Forbes, Ronald E. Dahl, Neal D. Ryan, Greg J. Siegle, Cecile D. Ladouceur, Jennifer S. Silk   +6 more
openalex   +2 more sources

Youth Lead the Change: Participatory Budgeting [PDF]

, 2005
This evaluation report examines the Youth Lead the Change process in its third year, drawing on qualitative and quantitative data from a variety of sources.
Augsberger, Astraea, Collins, Mary, Gecker, Whitney, Lusk, Katharine, Dougher, Meaghan   +4 more
core