Results 101 to 110 of about 121,098 (314)

Dual Physiological Barriers Bypassed by a Silk‐Based Supramolecular Protein Delivery Platform for Neuroinflammation Mitigation in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
A supramolecular nanocomplex based on phenolic‐modified silk sericin is developed to deliver antioxidant enzymes across the blood–brain barrier and escape lysosomal degradation. This dual‐barrier‐crossing system reduces neuroinflammation and improves cognitive performance in Alzheimer's disease mouse model, offering a promising strategy for protein ...
Doudou Hu   +5 more
wiley   +1 more source

Soviet Youth Films under Brezhnev: Watching Between the Lines [PDF]

open access: yes, 2013
The central argument of my dissertation emerges from the idea that genre cinema, exemplified by youth films, became a safe outlet for Soviet filmmakers’ creative energy during the period of so-called “developed socialism.” A growing interest in youth ...
Klimova, Olga
core  

National Youth Social Action Survey, 2016 [PDF]

open access: yes, 2020
copyright UK Data Service and data collection copyright owner.The National Youth Social Action Survey was established in 2014 to measure the extent to which 10 to 20 year olds are taking part in social action in the UK. The survey was commissioned by the
Department for Digital, Culture, Media and Sport
core  

Race in the age of tribeless youth culture: Rick Famuyiwa’s Dope (2015) and recent shifts in African-American pop culture [PDF]

open access: yes, 2017
This article posits Rick Famuyiwa’s 2015 film Dope as a site of convergence for broader shifts in recent African-American pop culture against the backdrop of post-racial ideology.
Gazi, J.
core   +1 more source

A Viscous DES‐AAV‐Foxo1 Delivery System With High Transfection Efficiency for the Treatment of Corneal Endothelial Dysfunction by Restoring Mitochondria‐ER Contacts

open access: yesAdvanced Science, EarlyView.
High glucose triggers corneal endothelial dysfunction by impairing FOXO1‐mediated ITPR1 transcription, leading to disrupted mitochondria‐associated membrane (MAM) integrity and defective ER‐to‐mitochondria Ca2+ transfer. This study develops an innovative viscous DES‐AAV‐Foxo1 delivery system with enhanced transfection efficiency. This non‐invasive gene
Hongran Zhao   +10 more
wiley   +1 more source

Survey of integrated approach to basic services and model villages [PDF]

open access: yes, 1980
The focus of the agents of development and modernization in any developing country is on the rural areas. This is understandable when it is realised that the sector forms 80 percent of its population and are inhabited by vulnerable groups, that arc ...
FEDERAL Ministry of Social Development, Youth and Culture
core   +1 more source

National Youth Social Action Survey, 2018 [PDF]

open access: yes, 2020
copyright UK Data Service and data collection copyright owner.The National Youth Social Action Survey was established in 2014 to measure the extent to which 10 to 20 year olds are taking part in social action in the UK. The survey was commissioned by the
Department for Digital, Culture, Media and Sport
core  

The potential for civil resilience. Staging inequalities in a stigmatized neighborhood [PDF]

open access: yesFilozofija i Društvo
Currently, Sweden is a society marked by growing anti-immigrant sentiments and residential stigmatization. As a result, the symbolic and social gaps between in-groups and out-groups are widening.
Lund Anna   +2 more
doaj   +1 more source

High‐Performance Prevascularized SHED‐Laden rGO@Hydrogel Achieves Optimized Diabetic Bone Defect Repair

open access: yesAdvanced Science, EarlyView.
A high‐performance 3D scaffold integrating rGO and SHEDs is developed to overcome impaired healing in diabetic bone defects. By driving extracellular matrix remodeling, rGO creates a pro‐angiogenic niche that significantly accelerates in vitro vascular network formation.
Can Zhang   +12 more
wiley   +1 more source

CD44‐Targeting Hydroxyapatite Nanoparticles (HAP) Induce Mitochondrial Dysfunction‐Driven PANoptosis and Immunogenic Cell Death (ICD) via Ca Overload in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
ABSTRACT Colorectal cancer (CRC) remains therapeutically challenging due to high metastasis, recurrence, and immunotherapy resistance driven by tumor microenvironment‐mediated immune evasion. Immunogenic cell death (ICD) offers a promising strategy to reshape the immune microenvironment, yet existing ICD inducers suffer from poor targeting efficiency ...
Yao Xiao   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy