Results 171 to 180 of about 1,801,862 (314)

Place-Based Developmental Research: Conceptual and Methodological Advances in Studying Youth Development in Context. [PDF]

Monogr Soc Res Child Dev, 2023
Witherspoon DP, White RMB, Bámaca MY, Browning CR, Leech TGJ, Leventhal T, Matthews SA, Pinchak N, Roy AL, Sugie N, Winkler EN.   +10 more
europepmc   +1 more source

Large‐Scale Quantitative Morphometry of Platelet α‐Granules via SIM Super‐Resolution Microscopy for Cancer Liquid Biopsy

Advanced Science, EarlyView.
ABSTRACT Blood‐based liquid biopsies hold transformative potential for non‐invasive cancer management, but current approaches relying on rare circulating tumor components limit their broad clinical utility. Platelets, abundant in blood and mediating diverse cancer‐associated responses, represent a compelling yet largely unexplored alternative.
Yan Ma, Huan Deng, Zelin Liu, Simei Zhong, Liangliang Wang, Mu He, Ning Jing, Lihua Dai, Yuzhen Basang, Xiao‐Yu Hu, Changyi Zhang, Huimin Zeng, Haoren Shao, Zhe Yang, Shanshan Zhao, Xiaohai Hu, Chuanjie Zhang, Xiaowei Wu, Jing Xu, Shaoqun Zeng, Jing Yuan, Qiang Li, Ziwei Qu, Zhenya Hong, Lingjuan Chen, Hanhua Dong, Jia Guo, Zhiqiang Han, Yu‐Hui Zhang   +28 more
wiley   +1 more source

Lessons Learned from Co-Designing a Digital Health App for Foster Youth: Development and Usability Study. [PDF]

JMIR Form Res
Folk JB, Gonzalez JC, Del Cid MV, McBride E, Lundberg T, Czopp A, Ezimora I, Fortuna LR, Tolou-Shams M.   +8 more
europepmc   +1 more source

SETD1A Regulates Glycolysis and Senescence of Nucleus Pulposus Cells via H3K4me3–HELZ2/PPARα‐HIF1α Axis to Drive Intervertebral Disc Degeneration

Advanced Science, EarlyView.
SETD1A is a key epigenetic regulator in NPCs during IDD. In normal NPCs, it sustains H3K4me3–HELZ2/PPARα–HIF1α signaling to maintain glycolytic energy metabolism and proliferation. In degenerated NPCs, reduced SETD1A disrupts this axis, impairing glycolysis and accelerating senescence, highlighting a promising therapeutic target for IDD.
Jiawei Fu, Xue Leng, Jiang Long, Zhengao Liao, Xiaoqin An, Xuezheng Ai, Dan Long, Changqing Li, Bo Huang, Yue Zhou, Shiwu Dong, Chencheng Feng   +11 more
wiley   +1 more source

Integrating Self-Determination Theory and Continuous Glucose Monitoring: Promoting Youth Development Among Campers with Type 1 Diabetes. [PDF]

Behav Sci (Basel)
Hill E, Arrington B, Harvey T, Barmoh A, Williams R, Hill L.   +5 more
europepmc   +1 more source

The Landscape and Regulation of Histone Crotonylation in Mammalian Gametes and Early Embryos

Advanced Science, EarlyView.
Histone crotonylation undergoes a genome‐wide transition from broad domains to canonical narrow peaks during minor zygotic genome activation (ZGA). This remodeling is required for proper major ZGA and blastocyst formation. Disruption of this transition by transcriptional inhibition, metabolic perturbation, or HDAC1 dysfunction impairs embryonic ...
Shenli Yuan, Yelian Yan, Yalin Liang, Kanghua Zhong, Zhican Fu, Xiaobo Wang, Chao Liu, Tao Huang, Keliang Wu   +8 more
wiley   +1 more source

Positive youth development through taekwondo: a journey to the black belt. [PDF]

Front Psychol
Lee Y, Lim S.
europepmc   +1 more source

Retina‐Inspired Bi‐Based Terahertz Photonic Neuromorphic Devices

Advanced Science, EarlyView.
Combined with effective band alignment and substrate engineering, bismuth materials are introduced to form terahertz photonic bio‐inspired devices with picosecond short‐term plasticity to enable multi‐scene visual perception. Thus obtained hardware through the terahertz optical neural network (THz‐ONN) demonstrates high recognition accuracy, providing ...
Pujing Zhang, Donggang Xie, Longyu Shi, Mengyuan Wang, Huiwen Shi, Yu Wu, Menglei Li, Guangwei She, Peijie Wang, Wensheng Shi, Cunlin Zhang, Kuijuan Jin, Guozhen Yang, Qingli Zhou, Chen Ge   +14 more
wiley   +1 more source

The Role of Social Support and Positive Youth Development Attributes in Family Resilience Processes: an Actor-Partner Interdependence Approach. [PDF]

J Youth Adolesc
Zhang Q, Yu L, Ren Y.
europepmc   +1 more source

Multifunctional Eutectic Mixtures Enable Integrated Recovery of U, Pu, and Sr From Nuclear Waste

Advanced Science, EarlyView.
A novel class of multifunctional eutectic mixtures, crafted from crown ether and organophosphorus molecules, achieves highly efficient, simultaneous recovery of uranium, plutonium, and strontium from nuclear waste. The material operates via a dual “coordination‐encapsulation” mechanism within self‐assembled reverse‐micelle structures, offering a ...
Yifan Wang, Yanjun Lv, Qilong Tang, Huaixin Hao, Jianfeng Jia, Gang Ye, Jing Chen, Chao Xu, Zhipeng Wang   +8 more
wiley   +1 more source