Results 171 to 180 of about 373,181 (317)

Exploring digital interaction and positive youth development in a sample of Spanish undergraduates. [PDF]

AIMS Public Health
López-Bermúdez E, Tomé G, Gómez-Baya D.   +2 more
europepmc   +1 more source

Youth mentoring and adult-youth relationships: The importance of context

, 2009
This study is about programmes that foster adult-youth relationships and more specifically about the community context necessary for such programmes to flourish.
Brooker, Miriam
core  

CD44‐Targeting Hydroxyapatite Nanoparticles (HAP) Induce Mitochondrial Dysfunction‐Driven PANoptosis and Immunogenic Cell Death (ICD) via Ca Overload in Colorectal Cancer

Advanced Science, EarlyView.
ABSTRACT Colorectal cancer (CRC) remains therapeutically challenging due to high metastasis, recurrence, and immunotherapy resistance driven by tumor microenvironment‐mediated immune evasion. Immunogenic cell death (ICD) offers a promising strategy to reshape the immune microenvironment, yet existing ICD inducers suffer from poor targeting efficiency ...
Yao Xiao, Yuxuan Yang, Haosen Qiu, Jia Yang, Hao Liang, Zhaojun Jiang, Xiao Tong, Yongying Li, Qunfeng Huang, Jiaming Wu, Tian Lin, Jiang Yu, Min Liang   +12 more
wiley   +1 more source

Family functioning and mobile phone dependency among adolescents: the mediating role of positive youth development and the moderating effect of physical activity. [PDF]

BMC Psychol
Luo F, Du Y, Sun Q, Peng N, Li Y.
europepmc   +1 more source

Transposase‐Assisted Donor Tethering Boosts Large‐Fragment HDR in Plants

Advanced Science, EarlyView.
A transposase‐assisted donor tethering strategy is developed to enhance homology‐directed repair in plants. By recruiting donor DNA to double‐strand breaks and synergizing with repair pathway reprogramming and transcription‐coupled donor design, this system markedly improves large‐fragment targeted insertion efficiency, providing a robust platform for ...
Sha Wei, Kai Zhang, Shuke Deng, Jinjie Chen, Xiaomei Huang, Jingfei Guo, Yuqing Wu, Yingjie Guo, Zhen Liang   +8 more
wiley   +1 more source

Promoting Positive Youth Development with Adolescent Boys in UK Schools: A Theory-Driven Evaluation of the "Becoming a Man" Programme. [PDF]

J Prev (2022)
Green F, Preece C, Allen K, Manzi S, Mannes J, Callaghan L, Berry V, de Lima ES, Woodburn A, Hobbs T, Harris J, Axford N.   +11 more
europepmc   +1 more source

Place-Based Developmental Research: Conceptual and Methodological Advances in Studying Youth Development in Context. [PDF]

Monogr Soc Res Child Dev, 2023
Witherspoon DP, White RMB, Bámaca MY, Browning CR, Leech TGJ, Leventhal T, Matthews SA, Pinchak N, Roy AL, Sugie N, Winkler EN.   +10 more
europepmc   +1 more source

Decoding Spatial Heterogeneity and Multi‐Omics Regulation with Hierarchical Graph Learning

Advanced Science, EarlyView.
ABSTRACT Recent advances in spatial multi‐omics technologies have enabled the simultaneous profiling of multiple molecular layers within the same tissue slice, providing unprecedented opportunities to investigate tissue spatial organization. However, most existing computational methods identify spatial domains in a purely data‐driven manner, rarely ...
Jiazhou Chen, Jiahui Xie, Yi Liao, Junyu Li, Longqi Liu, Xin Gao, Hongmin Cai   +6 more
wiley   +1 more source

Lessons Learned from Co-Designing a Digital Health App for Foster Youth: Development and Usability Study. [PDF]

JMIR Form Res
Folk JB, Gonzalez JC, Del Cid MV, McBride E, Lundberg T, Czopp A, Ezimora I, Fortuna LR, Tolou-Shams M.   +8 more
europepmc   +1 more source

Lighting up Macrophage Reprogramming Assists Immunosuppressive Niche Modulation in Primary Tumors and Tumor‐Draining Lymph Nodes of Breast Cancer

Advanced Science, EarlyView.
This study develops an intelligent NIR‐II‐responsive nanoplatform to combat immunosuppression in breast cancer. It enables real‐time visualization of macrophage activity via “off‐on” fluorescence while simultaneously reprogramming macrophages through the CSF‐1R and CD47‐SIRPα pathways.
Yingbo Li, Di Chang, Jie Yang, Ying Bai, Min Chen, Daoshuang Li, Zuoyu Xu, Jiaxin Yuan, Xiaoxuan Xu, Zhiqi Zhang, Yize Li, Zixin Chen, Jinbing Xie, Zebin Xiao, Shenghong Ju   +14 more
wiley   +1 more source