Results 201 to 210 of about 1,801,862 (314)

A Viscous DES‐AAV‐Foxo1 Delivery System With High Transfection Efficiency for the Treatment of Corneal Endothelial Dysfunction by Restoring Mitochondria‐ER Contacts

Advanced Science, EarlyView.
High glucose triggers corneal endothelial dysfunction by impairing FOXO1‐mediated ITPR1 transcription, leading to disrupted mitochondria‐associated membrane (MAM) integrity and defective ER‐to‐mitochondria Ca2+ transfer. This study develops an innovative viscous DES‐AAV‐Foxo1 delivery system with enhanced transfection efficiency. This non‐invasive gene
Hongran Zhao, Xiaoyu Li, Hongwei Wang, Zongyi Li, Qun Wang, Yangyang Zhang, Xu Jing, Xia Qi, Qingjun Zhou, Shengqian Dou, Lixin Xie   +10 more
wiley   +1 more source

Values Scale for Positive Youth Development in Sport. [PDF]

Eur J Investig Health Psychol Educ
Berengüí R, Parra-Plaza FJ, Castejón MÁ.   +2 more
europepmc   +1 more source

Ethical and Frugal Approaches to Animal Experimentation in Bioelectronics and Neural Engineering—An Invertebrate Renaissance?

Advanced Electronic Materials, EarlyView.
Invertebrates are the classic neuroscience models and should make a comeback. Invertebrate organisms can be a more ethical and cost‐effective way to move bioelectronics research forward more rapidly. ABSTRACT The accelerating development of bioelectronic neural interfaces has brought increased attention to ethical considerations surrounding in vivo ...
Eric Daniel Głowacki
wiley   +1 more source

The influence of social determinants and 5Cs of positive youth development on the mental health of Chilean adolescents. [PDF]

BMC Psychol
Marín-Gutiérrez M, Caqueo-Urízar A.
europepmc   +1 more source

Capacitive versus Faradaic Microelectrodes for Extracellular Stimulation: A Fully Coupled FEM–Hodgkin–Huxley Study of Thresholds and Current Redistribution

Advanced Electronic Materials, EarlyView.
A fully coupled FEM–HH model shows that ideally capacitive microelectrodes can achieve lower charge‐density thresholds than Faradaic contacts under current‐controlled stimulation. The advantage stems from the dynamics of surface current density on capacitive interfaces, which redirects current beneath adherent neurons.
Aleksandar Opančar, Eric Daniel Głowacki, Vedran Đerek   +2 more
wiley   +1 more source

Adaptation of a positive youth development program in the community of Guangaje, Cotopaxi, Ecuador. [PDF]

BMJ Paediatr Open
Espinosa IM, Bahamonde M, Ilaquiche R, Wood DL.   +3 more
europepmc   +1 more source

Depth‐of‐Discharge‐Dependent Chemical Evolution in Sulfurized Polyacrylonitrile Cathodes for Ether‐Based Room‐Temperature Sodium–Sulfur Batteries

Advanced Energy Materials, EarlyView.
Sulfurized polyacrylonitrile (SPAN) is investigated as a cathode for room‐temperature Na–S batteries in ether‐based electrolytes under controlled discharge depths. Depth‐of‐discharge‐dependent structural evolution reveals that deep discharge below 1.0 V destabilizes SPAN structure, alters polysulfide equilibria, and promotes sodium dendrite formation ...
Liwen Yang, Angelina Sarapulova, Bercis Pektas, Rong Li, Hatice Mutlu, Sonia Dsoke   +5 more
wiley   +1 more source

Co-creating a youth development survey with racial, ethnic, and gender diverse young people: Examining psychometric properties and measurement invariance. [PDF]

J Res Adolesc
Jones TM, Lea CH, Malorni A, Crumé HJ, Grodinsky L, Kebaya OE.   +5 more
europepmc   +1 more source

Enhancing Elderly Health Through Physical Activities: Insights From a Global Bibliometric Review, 1900–2023

AGING MEDICINE, EarlyView.
Bibliometric analysis reveals rising global research on physical activity and elderly health, dominated by developed nations. Key hotspots include healthy aging, physical activity's mental health benefits, and VR exercise interventions. Promoting physical activity is vital for healthy aging, requiring greater technology integration and research from ...
Hongman Wang, Bo Xie, Can Liu, Yifan Song   +3 more
wiley   +1 more source

School Suspension as a Predictor of Young Adult Homelessness: The International Youth Development Study. [PDF]

J Prev (2022)
Heerde JA, Bailey JA, Merrin GJ, Raniti M, Patton GC, Toumbourou JW, Sawyer SM.   +6 more
europepmc   +1 more source