Results 51 to 60 of about 13,927,111 (195)

Supramolecular Degraders: An Emerging Paradigm in Targeted Protein Degradation

Advanced Science, EarlyView.
Dynamic supramolecular assembly reshapes targeted protein degradation by coordinating modular degrader construction, delivery, functional integration, and intracellular assembly or activation across proteasomal, endosomal–lysosomal, and autophagy–lysosomal pathways.
Kongjun Liu, Xue Yuan, Yan Zhou, Rui Yuan, Shaocheng Xie, Yong Chen, Peiyi Wang, Jianmei Gao, Qihai Gong   +8 more
wiley   +1 more source

BRINGING OUT THE “CAL” IN GLOCAL: SITUATING SUBCULTURE AND DIGITAL SUBCULTURES IN TURKISH YOUTH

Glocalism: Journal of Culture, Politics and Innovation
In a globalized postmodern world, the metanarratives of modernity are contested and have been paving the way for a patchwork of cultures and subcultures.
faydogan Filiz Aydogan Boschele
doaj   +1 more source

Use Cases for Access to Internet Archives

, 2006
This report identifies and specifies a number of possible usage scenarios of an Internet ...
International Internet Preservation Consortium. Access Working Group
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Chemotherapy‐Activated GSK3β‐DNMT1 Signaling Upregulates CD47 to Evade Macrophage Phagocytosis and Drive Temozolomide Resistance in Glioblastoma

Advanced Science, EarlyView.
Temozolomide treatment activates GSK3β, driving DNMT1 phosphorylation, destabilization, and CD47 promoter hypomethylation in glioblastoma. This epigenetic shift upregulates CD47, enabling TMZ‐treated GBM cells to evade macrophage phagocytosis, survive chemotherapy, and acquire resistance.
Jie Li, Shuai Ying, Yi Zhang, Jingjing Wang, Quan Wan, Lingli Gong, Daxing Xu, Zhenkun Yang, Hongnian Lu, Ying Yin, Xiangming Fang, Zhening Pu   +11 more
wiley   +1 more source

Learning and institutional support for youth in higher education institutions during the COVID-19 pandemic in South Africa

Frontiers in Education
IntroductionAs higher education institutions (HEIs) moved from in-person to online learning during the COVID-19 pandemic, various challenges were presented.
Natisha Dukhi, Ronel Sewpaul, Nompumelelo P. Zungu, Nompumelelo P. Zungu, Tholang Mokhele, Sibusiso Sifunda   +5 more
doaj   +1 more source

Solution‐Processed Multi‐Junction Optoelectronic Synapses for Mode‐Switchable SWIR Neuromorphic Vision Sensing

Advanced Science, EarlyView.
A novel bias‐programmable shortwave infrared (SWIR) vision sensor is developed using multi‐junction colloidal quantum dots (QDs). Under varying applied voltage, the back‐to‐back rectifying junctions effectively tune trapping centers to switch the device between high‐speed photodetector and persistent synapse modes.
Zhuoyang He, Dae Yang Oh, Yi Ji, Yanyan Li, Chengwei Shan, Soong Ju Oh, Tianshuo Zhao   +6 more
wiley   +1 more source

Light‐Gated Control of Brownian Rotation by a Molecular Motor

Angewandte Chemie, EarlyView.
A light‐driven molecular motor acts as a reversible steric gate for a nearby Brownian rotor. Photoisomerization switches the rotor between fast and hindered rotational regimes by modulating steric congestion around the rotational axis. The motor–rotor architecture enables a five‐order‐of‐magnitude difference in the rotational barrier, demonstrating ...
Lukáš Severa, Kateřina Bezděková, Katarina Majerová Varga, Guillaume Bastien, Miroslav Stroka, Ivana Císařová, Martin Dračínský, Jiří Kaleta   +7 more
wiley   +2 more sources

Multicultural services for youth offenders

, 2010
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF title page (viewed on Mar.21, 2011)"September

core  

An Injectable, Self‐Expanding Hemostatic Foam for Field‐Compatible Postpartum Hemorrhage Management

Advanced Science, EarlyView.
Postpartum hemorrhage is the leading cause of maternal death worldwide, yet many treatments are hard to use outside well‐equipped hospitals. This work introduces an easy‐to‐use device that rapidly delivers a degradable foam into the uterus. The foam stops bleeding through pressure and clotting support, offering a practical option for low‐resource ...
Charlotte Meyer, Noël Strasser, Ilakkiya Ravindrarajah, Elsa Wrenger, Kristian Ivkovic, Jan Ševčík, Sima Šarčević, Lenka Červenková, Jáchym Rosendorf, Václav Liška, Alexandre H. Anthis, Thomas Rduch, Inge K. Herrmann   +12 more
wiley   +1 more source

Social well-being and information behavior of the youth in the Republic of Khakassia

RUDN journal of Sociology, 2015
The article considers social well-being and information behavior of the youth in the Republic of Khakassia focusing on the youth expectations and aspirations, relationships with the state, desires to be useful to one’s social circle, society and the ...
T B Shigolakova
doaj