Results 131 to 140 of about 427,440 (290)

SPEED ENDURANCE TRAINING IN ELITE YOUTH SOCCER PLAYERS [PDF]

, 2019
The physical demands of soccer match play have significantly increased in recent years. As such, training methods must evolve to ensure players are able to cope with these demands over the course of a season. Speed endurance training is recommended to improve physical performance in elite soccer players, however scientific investigations into different
openaire   +1 more source

Promoter Hypermethylation‐Induced Silencing of FXYD1 Drives Breast Cancer Metastasis via DDX5‐Mediated Wnt/β‐Catenin Pathway Activation

Advanced Science, EarlyView.
This study identifies FXYD1 as an epigenetically silenced tumor suppressor in breast cancer. DNA methylation turns off the gene FXYD1 in breast cancer, and low levels predict worse outcomes. Restoring FXYD1 limits breast cancer cells proliferation and metastasis. In the nucleus, FXYD1 recruits the E3 ligase MAEA to K63‐ubiquitinate DDX5 for proteasomal
Ping Wen, Fanli Qu, Long Wang, Qing Shao, Sisi Li, Yang Qin, Dongping Jiang, Senmiao Zhang, Jiangdong Sui, Guanwen Wang, Ningning Zhang, Xiaohua Zeng   +11 more
wiley   +1 more source

Efecto del saque en suspensión sobre la construcción del ataque en el voleibol. (Jump serve incidence on the attack phase in the Spanish under-14 volleyball).

Revista Internacional de Ciencias del Deporte, 2011
ResumenEl presente estudio pretende observar la incidencia del saque en suspensión sobre la construcción del ataque en el voleibol en categoría infantil.
Manuel González Ortiz, Julia León Rodríguez, Roberto Vavassori, Aurelio Ureña Espa   +3 more
doaj  

Nutrition as a missing piece in the development of youth male soccer players: a scoping review and future directions

Biology of Sport
The literature on nutrition in soccer has extensively focused on adult male and female soccer players, while knowledge regarding nutritional issues in youth soccer players remains limited. This review aims to summarize the findings related to nutritional
Diogo Martinho, Oliver Gonzalo-Skok, Karim Chamari, Adam Field, Filipe Clemente, André Rebelo, Élvio Gouveia, Vitor Hugo Teixeira, Piotr Zmijewski, Pedro Mendes, Pedro Campos, Hugo Sarmento   +11 more
doaj   +1 more source

Development‐based In Vivo Bioreactor Strategy for Challenging Senescent Bone Reconstruction

Advanced Science, EarlyView.
We present a development‐based in vivo bioreactor strategy to generate rejuvenated bone grafts (vBR‐Bone) within aged hosts. By enclosing vBR‐Bone fragments within an asymmetric biomimetic periosteum, segmental femoral defects in aged mice were successfully repaired within 6 weeks. Mechanistically, the multifactors of vBR‐Bone reconstitute a remodeling
Wenchao Zhang, Kai Dai, Tong Shen, Zehua Gao, Fengying Yan, Yuke Feng, Xuanlin Wang, Shaozhen Zhang, Jing Wang, Changsheng Liu   +9 more
wiley   +1 more source

Dual‐Physical‐Field Nanocatalysis: Injectable Hydrogel Enables Piezo‐Photothermal Synergy for Breast Cancer Therapy

Advanced Science, EarlyView.
ABSTRACT Piezocatalytic therapy (PCT) harnesses mechanical energy to generate tumor‐lethal reactive oxygen species (ROS), but its efficacy is limited by rapid electron‐hole recombination and poor intratumoral retention. To overcome these limitations, we engineered heterostructured BiOCl@CuO nanosheets embedded in an injectable, conductive ...
Can Tian, Shihan Xiao, Xuan Chen, Danni Zhang, Zizhen Liu, Jing Wang, Ning Xie, Wei Li   +7 more
wiley   +1 more source

Selection biases in elite youth handball: early maturation compensates for younger relative age

Frontiers in Sports and Active Living
Talent selections in youth sports are frequently biased regarding the maturation and relative age of the players, with preference given to more mature and relatively older players.
Lutz Thieschäfer, Lutz Thieschäfer, Jörg Schorer, Jochen Beppler, Dirk Büsch   +4 more
doaj   +1 more source

Visual exploratory activity in youth soccer players [PDF]

, 2013
Eldridge, David, Pulling, Craig, Robins, Matthew T.   +2 more
core   +2 more sources

Dual Covalent Targeting of STING Cysteines 292/309 Disrupts Functional Oligomerization and Enables Potent Antagonist Development

Advanced Science, EarlyView.
We report a rational design strategy for STING antagonists by dual covalent targeting of Cys292/309 in its C‐terminal domain, directly preventing functional oligomerization. Through covalent warhead repurposing, we identified P005091 and revealed its unique dual‐cysteine mechanism.
Yuxuan Zhao, Ling Huang, Wenjing Qin, Bin Zhang, Yang Yang, Xue Chen, Xiaoquan Wang, Weilin Zhou, Feiyang Chen, Zhenyu Li, Liyuan Le, Yiqiu Zhang, Zhen Xiang, Lu Zhang, Fei Wang, Dan Lei, Zi‐zhe Cai, Ying Gao, Yong Chen, Xuecen Wang, Junmin Quan, Shuixing Zhang, Xianzhang Bu, Xin Yue   +23 more
wiley   +1 more source

SAA/FPR2 Signaling Between Pericentral Hepatocytes and Macrophages Exacerbates Zonated Liver Transplant Injury

Advanced Science, EarlyView.
After liver transplantation, ischemia‐reperfusion injury is more severe in pericentral regions. Multiomic analyses of human grafts and mouse models identify FOXO1 activation in pericentral hepatocytes as an upstream driver of SAA secretion. SAA recruits and activates FPR2+ macrophages, amplifying local inflammation. Amilo‐5MER inhibits SAA bioactivity,
Feng Zhang, Rong Li, Tingting Wang, Jianhao Zhang, Zhengqi Wu, Qiang You, Xuying Liu, Cuicui Xiao, Jiebin Zhang, Haitian Chen, Jiaqi Xiao, Jia Yao, Jun Zheng, Yingcai Zhang, Hua Li, Shuhong Yi, Yang Yang, Qi Zhang, Xiaofeng Yuan, Yasong Liu   +19 more
wiley   +1 more source