Results 121 to 130 of about 760,246 (312)

An Examination of Gender and Race Differences in Youth Smoking Responsiveness to Price and Tobacco Control Policies [PDF]

open access: yes
Nationally representative studies consistently report significant gender and racial differences in youth smoking rates, although little research has been done to explain why. In this paper we examine one possible source for this variation: differences in
Frank J. Chaloupka   +1 more
core  

Electron Delocalization Induced by 3d–4f Orbital Hybridization of Co─Ce Atom Pairs Toward Enhanced Electromagnetic Wave Attenuation and Antibacterial Performance

open access: yesAdvanced Science, EarlyView.
Co─Ce dual atomic configuration anchored on the surface of NC matrix has been constructed to regulate the local electron structure. The higher occupied states induced by the Co 3d‐Ce 4f orbital hybridization facilitate the formation of polarized electric fields, which in turn strengthens the polarization relaxation and partially repairs the effective ...
Da Li   +8 more
wiley   +1 more source

Network structures and laws of youth policy of Austria. [PDF]

open access: yes, 2012
У статті йдеться про молодіжну політику Австрії, розглядаються державні структури національного, регіонального та місцевого рівня, що займаються питанням молоді у країні.
Najdych, M. A.   +1 more
core  

SETD1A Regulates Glycolysis and Senescence of Nucleus Pulposus Cells via H3K4me3–HELZ2/PPARα‐HIF1α Axis to Drive Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
SETD1A is a key epigenetic regulator in NPCs during IDD. In normal NPCs, it sustains H3K4me3–HELZ2/PPARα–HIF1α signaling to maintain glycolytic energy metabolism and proliferation. In degenerated NPCs, reduced SETD1A disrupts this axis, impairing glycolysis and accelerating senescence, highlighting a promising therapeutic target for IDD.
Jiawei Fu   +11 more
wiley   +1 more source

The Landscape and Regulation of Histone Crotonylation in Mammalian Gametes and Early Embryos

open access: yesAdvanced Science, EarlyView.
Histone crotonylation undergoes a genome‐wide transition from broad domains to canonical narrow peaks during minor zygotic genome activation (ZGA). This remodeling is required for proper major ZGA and blastocyst formation. Disruption of this transition by transcriptional inhibition, metabolic perturbation, or HDAC1 dysfunction impairs embryonic ...
Shenli Yuan   +8 more
wiley   +1 more source

Multifunctional Eutectic Mixtures Enable Integrated Recovery of U, Pu, and Sr From Nuclear Waste

open access: yesAdvanced Science, EarlyView.
A novel class of multifunctional eutectic mixtures, crafted from crown ether and organophosphorus molecules, achieves highly efficient, simultaneous recovery of uranium, plutonium, and strontium from nuclear waste. The material operates via a dual “coordination‐encapsulation” mechanism within self‐assembled reverse‐micelle structures, offering a ...
Yifan Wang   +8 more
wiley   +1 more source

Supporting Transgender and Gender Diverse Youth: Protection Against Emotional Distress and Substance Use. [PDF]

open access: yesAm J Prev Med, 2018
Gower AL   +6 more
europepmc   +1 more source

Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus

open access: yesAdvanced Science, EarlyView.
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan   +11 more
wiley   +1 more source

Voices from Urban Africa: The Impact of Urban Growth on Children [PDF]

open access: yes, 2012
Urban poverty -- and its impact on children -- is often overlooked and misunderstood. More than half of the world's population now lives in cities. Each year the number of urban residents increases by nearly 60 million.1 By 2050, it is projected that two
Anne Stotler   +2 more
core  

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