Results 251 to 260 of about 1,295,685 (397)

ADAMTS9‐AS2 Disrupts Docetaxel‐Resistance in Castration‐Resistant Prostate Cancer via Stemness Suppression and Ferroptosis Induction

open access: yesAdvanced Science, EarlyView.
This study uncovered a dual‐track mechanism by which ADAMTS9‐AS2 overcame chemoresistance in CRPC: suppressing cancer stemness through the FOXF2/TGF‐β2 pathway, and triggering ferroptosis via competitive SLC7A11 sequestration. Polymeric materials co‐targeting these vulnerabilities further boost docetaxel sensitivity, highlighting a compelling strategy ...
Ji Liu   +12 more
wiley   +1 more source

Delivering project SCORE in competitive youth sport settings. [PDF]

open access: yesFront Sports Act Living
Ferreira M   +5 more
europepmc   +1 more source

Giant Isotope Effect in Metal–Organic Frameworks Boosts Unprecedented Photo‐ and Radio‐Luminescence Enhancement

open access: yesAdvanced Science, EarlyView.
Deuterated MOFs in this work exhibited unprecedented giant luminescence isotope effect via O─H oscillator suppression, achieving maximal solid‐state materials emission enhancement. This yields significantly improved X‐ray detection sensitivity and imaging resolution, marking the first integration of MOFs with isotopic luminescence and opening new ...
Junhao Lu   +16 more
wiley   +1 more source

Dilution Effect for High‐Performance Multiple‐Component Near‐Infrared Organic Photodetectors

open access: yesAdvanced Science, EarlyView.
The dilution effect in multi‐component organic photodetector effectively suppresses non‐radiative decay and minimizes dark current, while energy‐level‐offset‐governed electron transfer between acceptors maintains efficient charge transport. This synergistic mechanism collectively enables remarkable device performance, including high detectivity and ...
Zhuang Li   +9 more
wiley   +1 more source

Youth Sport Specialization: Current Concepts and Clinical Guides. [PDF]

open access: yesHSS J
Sugimoto D   +3 more
europepmc   +1 more source

Cascade‐Responsive MXene@Cu‐MOF Heterostructure Integrates Antioxidant Activity, Infection Control, and Vascularization for Tracheal Repair

open access: yesAdvanced Science, EarlyView.
A cascade‐responsive MXene@Cu‐MOF/GelMA hydrogel is engineered as a “skeleton–backpack” platform for extensive tracheal repair. The MXene framework scavenges postoperative ROS and converts NIR light into mild hyperthermia, while the Cu‐MOF component provides pH/NIR‐responsive Cu2+ dosing for infection control, angiogenesis, and chondrogenesis.
Liang Guo   +8 more
wiley   +1 more source

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