To achieve efficient cancer cell death, a bowl‐shaped PDA@UiO‐66@DOX nanorobot drug‐delivery nanoplatform was developed. Near‐infrared irradiation not only drives the nanorobot to exhibit self‐thermophoretic motion and elevates temperature but also triggers Doxorubicin (DOX) release via hyperthermia, enhancing cancer cells uptake of DOX and thereby ...
Tong Lin +6 more
wiley +1 more source
Our study identifies the HDACs‐STAT3 axis as key regulator for M2 macrophage accumulation in DLBCL. We developed Chid@M2pep‐EVs/TP, a pH‐responsive drug delivery system for M2 macrophage specific chidamide administration. By coupling M2‐targeted chidamide with EVs‐mediated delivery, this system reprograms M2 to M1 via HDAC inhibition and STAT3 ...
Bo Dai +15 more
wiley +1 more source
Are we retaining our Maori talent? : representative youth netballers : a thesis presented in partial fulfilment of the requirements for the degree of Master of Education at Massey University [PDF]
A case study research method was employed to address the question of retention for Māori youth netballers. Despite the fact that young Māori are well populated in the junior age groups of representative netball, a decline at the senior representative ...
McCausland-Durie, Yvette
core
Relational intersection of youth sport participation and identity development [PDF]
Youth sport has continued to grow in attraction, particularly in the United States. Many youth, at younger and younger ages, are entering the confines of sport yet expansive research is still lacking in fully exploring the many facets that are a part of ...
Casey, Taylor Breann Moore
core +1 more source
Enhancing coach-parent relationships in youth sports: increasing harmony and minimizing hassle [PDF]
Frank Smoll and his colleagues should be commended on continuing to advance the worthy aim of making youth-sport participation more enjoyable. Indeed, the body of work generated by Smith and Smoll [e.g., 1], along with the more recent contributions of ...
MacLean, Kristy N., Rynne, Steven B.
core +1 more source
THE METHODS OF COORDINATION ABILITIES IMPROVEMENT OF FOOTBALL PLAYERS OF 14-15 YEARS OLD
In modern football the main volume of competitive activity is carried out in probabilistic and unexpected situations which demand from athletes the manifestation of resourcefulness, speed of reaction, ability to concentrate and switching of attention ...
F. Zereg, M. V. Zhiyyar, A. A. Ryazanov
doaj +1 more source
RETREG1‐Mediated Reticulophagy is Essential for Dendritic Cell Maturation and Function in Sepsis
Reticulophagy regulator 1 (RETREG1) maintains dendritic cell (DC) maturation and function in early sepsis. Mechanistically, activating transcription factor 6 (ATF6) acts as a direct transcription factor regulating RETREG1 expression in response to sepsis‐induced endoplasmic reticulum (ER) stress.
Ren‐Qi Yao +28 more
wiley +1 more source
HISTORICAL PRECONDITIONS OF THE DEVELOPMENT AND FORMATION OF SPORTS CONFLICTOLOGY
In the development of modern society, the growing interest in conflict and conflictology is known, which has several grounds for it. An important feature of modernity is the increase in the number of conflicts that arise in various spheres of social ...
A. Boussaha, M. V. Gillard
doaj
A longitudinal examination of coach and peer motivational climates in youth sport: Implications for moral attitudes, well-being, and behavioral investment. [PDF]
Embedded in achievement goal theory (Ames, 1992; Meece, Anderman & Anderman, 2006), this study examined how perceptions of coach and peer motivational climate in youth sport predicted moral attitudes, emotional well-being, and indices of behavioral ...
Ntoumanis, Nikos +2 more
core +3 more sources
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao +11 more
wiley +1 more source

