Results 211 to 220 of about 2,125,664 (226)

Evaluating Bicarbonate Electrolyzer Configurations for Energy‐Efficient Formate Production

Advanced Sustainable Systems, EarlyView.
Reactive carbon capture (RCC) with bicarbonate electrolyzers (BEs) offers an efficient alternative to gas‐fed CO2 electrolyzers by eliminating regeneration and pressurization steps. This study optimizes BE configurations and compares RCC chains to gas‐fed carbon chains for formate production.
Alessio Mezza, Juqin Zeng, Marco Etzi, Daniele Sassone, Fabrizio C. Pirri, Adriano Sacco   +5 more
wiley   +1 more source

Predicting Macrophage Spatial Localization from Single‐Cell Transcriptomes to Uncover Disease Mechanisms

Advanced Science, EarlyView.
This study presents a machine‐learning framework entitled MERLIN that infers the microanatomical localization of macrophages from single‐cell transcriptomic data in structured organs such as the kidney and brain. Applying this method to existing datasets from models of acute kidney injury and diabetic nephropathy uncovered spatially resolved insights ...
Junping Yin, Qi Mei, Hans‐Joachim Paust, Ning Song, Yu Zhao, Daniela Klaus, Melanie Eichler, Yijun Hua, Jie Qin, Weiting Cheng, Christina K. Weisheit, Veronika Lukacs‐Kornek, Isis Ludwig‐Portugall, Sibylle von Vietinghoff, Christian F. Krebs, Johanna Klughammer, Ulf Panzer, Christian Kurts, Jian Li   +18 more
wiley   +1 more source

<i>N</i>-Substitution effects on the conformations of iminosugar analogues of 1-deoxy-l-idose and 1-deoxy-l-iduronic acid. [PDF]

RSC Adv
Taglietti L, Palomba E, Lange H, Zoia L, Chiacchio MA, Legnani L, La Ferla B.   +6 more
europepmc   +1 more source

RIG‐I Mediated Neuron‐Specific IFN Type 1 Signaling in FUS‐ALS Induces Neurodegeneration and Offers New Biomarker‐Driven Individualized Treatment Options for (FUS‐)ALS

Advanced Science, EarlyView.
Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann, Theresa M. Wierschin, Stefanie Kretschmer, Banaja P. Dash, Aaron Held, Andrea Salzinger, Kevin Peikert, Anže Karlek, Hannes Glaß, Dajana Großmann, René Günther, Susanne Petri, Annekathrin Rödiger, David Brenner, Francisco Pan‐Montojo, Eleonora Aronica, Markus Kipp, Vitaly Zimyanin, Jared Sterneckert, Torsten Grehl, Noah D. Seebacher, Tobias M. Böckers, Alberto Catanese, Brian J. Wainger, Patrick Oeckl, Min Ae Lee‐Kirsch, Andreas Hermann   +26 more
wiley   +1 more source

Comparative Chromosomal Analysis of the Z Chromosome in South American Bird Species Shows a High Rate of Intrachromosomal Rearrangements. [PDF]

Genes (Basel)
Enguito MRC, Garnero ADV, Gunski RJ, de Souza MS, O'Connor RE, Srikulnath K, Singchat W, de Oliveira EHC, Romanov MN, Griffin DK, Kretschmer R.   +10 more
europepmc   +1 more source

Solution structure of Z-form DNA bound to a curaxin ligand CBL0137. [PDF]

Nucleic Acids Res
Liu F, Wang S, Xu Y.
europepmc   +1 more source

Synthesis of sulfanyl derivatives of 1,2,4-triazoles <i>via</i> an acid catalyzed intramolecular cyclization of isothiosemicarbazones: structural characterization, <i>E</i>/<i>Z</i> isomerism, mechanistic insights and <i>in vitro</i> cytotoxicity. [PDF]

RSC Adv
Snisha K, Karthikeyan MC, Bhuvanesh N, Arockiam AJV, Karvembu R.   +4 more
europepmc   +1 more source

Effects of Bisphosphonates on Bone Micro-Architecture of Children With Duchenne Muscular Dystrophy: A Prospective Comparative Study. [PDF]

J Cachexia Sarcopenia Muscle
Wang S, Dai Y, Meng L, Zhang Y, Sun L, Wang Y, Wang O, Jiang Y, Xia W, Xing X, Yu W, Li M.   +11 more
europepmc   +1 more source