Results 221 to 230 of about 14,410,842 (233)

The average individual genome: a survey of nearly 1 million whole-genome sequences. [PDF]

Genome Med
Wright HIW, Beaumont RN, Fasham J, Leslie JS, Chundru VK, Hall TS, Cannon SJ, Pagnamenta AT, Baple EL, Wood AR, Murray A, Jackson L, Weedon MN, Patel K, Hawkes G, Wright CF.   +15 more
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Modeling Exposure-Mortality Relationships for Indoor Heat. [PDF]

Risk Anal
Ibbetson A, Simpson C, Petrou G, Oikonomou E, Mavrogianni A, Gupta R, Davies M, Milojevic A.   +7 more
europepmc   +1 more source

Adjusting for Medication Use in GWAS and Its Impact on Mendelian Randomisation Analyses: An Example of Systolic Blood Pressure in UK Biobank. [PDF]

Genet Epidemiol
Yap AJY, Hanson AL, Griffith GJ, Sanderson E.   +3 more
europepmc   +1 more source

Numerical analysis of unsteady squeezing MHD flow of a ternary hybrid nanofluid between parallel rotating disks with Hall current and heat transfer reversal. [PDF]

Discov Nano
Rao S.
europepmc   +1 more source

Automated Tissue Classification and Candidate Biomarker Feature Extraction in Mass Spectrometry Imaging Based on Interpretable Deep Learning Algorithm. [PDF]

Rapid Commun Mass Spectrom
Xu G, Gan S, Guo B, Yang L.
europepmc   +1 more source