Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Accelerated Photogenerated Charge Separation Driven Synergistically by the Interfacial Electric Field and Work Function in Z-Scheme Zn-Ni<sub>2</sub>P/G-C<sub>3</sub>N<sub>4</sub> for Efficient Photocatalytic Hydrogen Evolution. [PDF]
Chen Q +8 more
europepmc +1 more source
Green synthesis of novel Z-scheme SnS2/HAp nanocomposite using Ocimum tenuiflorum leaf extract and investigation of its photocatalytic activity. [PDF]
Gadore V +3 more
europepmc +1 more source
A multi-functional novel Z-scheme ZnIn<sub>2</sub>S<sub>4</sub>/g-C<sub>3</sub>N<sub>5</sub> heterojunction catalyst for enhanced visible light active photocatalysis and antimicrobial action. [PDF]
Sahu PK +5 more
europepmc +1 more source
Preparation of a Z-scheme BiVO<sub>4</sub>/Cu<sub>2</sub>O/PPy heterojunction and studying its CO<sub>2</sub> reducing properties. [PDF]
Ren H +6 more
europepmc +1 more source
Solid-state electron-mediated z-scheme heterostructured semiconductor nanomaterials induce dual programmed cell death for melanoma therapy. [PDF]
Ren Y +11 more
europepmc +1 more source
Carbon Nanotubes as a Solid-State Electron Mediator for Visible-Light-Driven Z-Scheme Overall Water Splitting. [PDF]
Lin L +8 more
europepmc +1 more source
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