Results 41 to 50 of about 15,580 (299)

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

A Family of High Step-Up Quasi Z-Source Inverters with Coupled Inductor

Energies, 2020
With the continuous development of new energy, there is more and more research on step-up inverters in photovoltaic and wind power generation systems.
Yu Tang, Hao Sun, Shaoheng Wang
doaj   +1 more source

A Hysteresis Space Vector PWM for PV Tied Z-Source NPC-MLI With DC-Link Neutral Point Balancing

IEEE Access, 2021
The Photo-voltaic (PV) tied Z-source Neutral-point clamped multilevel inverter (Z-NPC-MLI) is used in solar grid connected applications due to its single stage conversion and better performance.
Suresh Kumar Annam, R. K. Pongiannan, N. Yadaiah   +2 more
doaj   +1 more source

Analysis and modeling of the Quasi-Z-Source-Inverter

IECON 2011 - 37th Annual Conference of the IEEE Industrial Electronics Society, 2011
This paper presents a dynamic average model of the Quasi-Z-Source Inverter (QZSI), based on the short term average values over one PWM-period, and the analysis of the possible switching states that can occur in the QZSI. The model is considerably descriptive since the modeling has been performed by analyzing the physical and functional relations with ...
Liske, A., Clos, G., Braun, M.
openaire   +3 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Analysis of Z-Source Inverter For Space Vector PWM Fed 3-Phase InductionMotor [PDF]

Engineering and Technology Journal, 2010
This paper presents analysis of operation and implementation of Z-source space vector pulse width modulation (SVPWM) inverter fed three phase induction motor. The Z-source is an alternative power conversion topology that can both buck and boost the input
Majid K. Al-Khatat
doaj   +1 more source

Evaluation of Resonant Damping Techniques for Z-Source Current-Type Inverter

, 2008
For the renewable energy sources whose outputs vary continuously, a Z-source current-type inverter has been proposed as a possible buck-boost alternative for grid-interfacing.
Loh, Poh Chiang, Vilathgamuwa, D. Mahinda, Vilathgamuwa, D.M., Gajanayake, C.J., Blaabjerg, Frede, Blaabjerg, Frede; id_orcid, Gajanayake, Chandana Jayampathi   +6 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Trans-Z-source Neutral Point Clamped inverter

, 2012
Transformer based Z-source (trans-Z-source) inverters are recently proposed by extending the traditional Z-source inverter with higher buck-boost capability as well as reducing the passive components at the same time.
D. Li, Loh, Poh Chiang, W. Mo, F. Blaabjerg, Li, D., P.C. Loh, Mo, W., Loh, P. C., Blaabjerg, Frede, Blaabjerg, Frede; id_orcid   +9 more
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source