Results 111 to 120 of about 2,146,019 (274)
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Research on Cascaded Three-phase quasi-Z Source Inverter
Kongzhi Yu Xinxi Jishu, 2017 It presented a LVC-qZSI(line voltage cascaded quasi-Z source inverter) which uses a multiplexed inverter topology cascaded by line voltage and its module unit is composesd by two modules: quasi-Z source network and three-phase inverter.
ZHANG Weiwei
doaj
Identifying P2P Users Using Traffic Analysis [PDF]
, 2009 Bakalářská práce se zaobírá možnostmi detekce uživatelů P2P sítí jako BitTorrent, DC++, Gnutella a jiné. Byla vytvořena aplikace, schopná detekovat tyto uživatele vícerými způsoby. Metoda kombinuje analýzu datové části paketu a analýzu síťového provozu a
Jalsovszky, Zoltán
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
A New Structure of Buck-Boost Z-Source Converter Based on Z-H Converter [PDF]
Journal of Operation and Automation in Power Engineering, 2016 In this paper, a new structure for buck-boost Z-source converter based on Z-H topology is proposed. The proposed converter consists of two LC networks similar to the conventional Z-source and Z-H converters.
E. Babaei, T. Ahmadzadeh
doaj
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
A new single magnetic core coupled-inductor based active switched Quasi Z-source inverter
Scientific ReportsThis paper presents a novel topology for Z-source inverters (ZSI). The new Z-Source network is based on the coupled-inductors and active switched boost. Features of the topology include high voltage boost ability, single magnetic-core, low voltage stress
Mohammadreza Zarrinehbafan +3 more
doaj +1 more source