Results 151 to 160 of about 7,369,874 (310)

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

Coefficient functionals for Sakaguchi-type-Starlike functions subordinated to the three-leaf function

Demonstratio Mathematica
A challenging part of studying geometric function theory is figuring out the sharp boundaries for coefficient-related problems that crop up in the Taylor-Maclaurin series of univalent functions.
Murugusundaramoorthy Gangadharan, Lupas Alina Alb, Alburaikan Alhanouf, El-Deeb Sheza M.   +3 more
doaj   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

FEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia, Eric Catalina‐Hernandez, Maialen Cabrerizo‐Idiazabal, Ramon Barnadas‐Rodríguez, Mario Lopez‐Martin, Alex Peralvarez‐Marin   +5 more
wiley   +1 more source

THE PRODUCT OF ANALYTIC FUNCTIONALS IN Z' [PDF]

Journal of the Korean Mathematical Society, 2008
Yang Zhang, Chenkuan Li, Ricky Tang, Manuel A. Aguirre   +3 more
openaire   +2 more sources

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Differential Production Cross Section ofZBosons as a Function of Transverse Momentum ats=1.8TeVTeV [PDF]

, 2000
B. Abbott, M. Āboliņš, Vyacheslav M. Abramov, B. S. Acharya, И. Адам, D. L. Adams, M. R. Adams, S. Ahn, V. Akimov, G. A. Alves, N. Amos, E. W. Anderson, M. M. Baarmand, V. Babintsev, L. Babukhadia, A. Baden, B. Baldin, S. Banerjee, J. Bantly, E. Barberis, P. Baringer, J. F. Bartlett, A. Belyaev, S. B. Beri, I. A. Bertram, V. A. Bezzubov, P. C. Bhat, V. Bhatnagar, M. Bhattacharjee, G. Blazey, S. Blessing, P. C. Bloom, A. Boehnlein, N. I. Bojko, F. Borcherding, C. Boswell, A. Brandt, R. Breedon, G. Briskin, R. Brock, A. Bross, D. Buchholz, В. С. Буртовой, J. M. Butler, W. Carvalho, D. Casey, Z. Casilum, H. Castilla-Valdez, D. Chakraborty, K. M. Chan, S. V. Chekulaev, W. Chen, D. K. Cho, S. Choi, S. Chopra, B. C. Choudhary, J. H. Christenson, M. Chung, D. R. Claes, A. R. Clark, W. G. Cobau, J. Cochran, L. Coney, W. E. Cooper, D. Coppage, C. Cretsinger, D. Cullen-Vidal, M. A. C. Cummings, D. Cutts, O. I. Dahl, K. Davis, K. De, K. Del Signore, M. Demarteau, D. Denisov, S. P. Denisov, H. T. Diehl, M. Diesburg, G. Di Loreto, Patrick Draper, Y. Ducros, L. Dudko, S. R. Dugad, A. Dyshkant, D. Edmunds, J. Ellison, V. D. Elvira, R. Engelmann, S. C. Eno, G. Eppley, P. Ermolov, O. V. Eroshin, J. Estrada, H. Evans, V. N. Evdokimov, T. Fahland, M. Fatyga, S. Fehér, D. Fein, T. Ferbel   +99 more
openalex   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source