Results 171 to 180 of about 7,607,900 (314)

An improved bound for negative binomial approximation with z-functions

, 2017
K. Teerapabolarn
openalex   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

THE VELOCITY FUNCTION OF DARK MATTER HALOS AT R = 20 kpc: REMARKABLY LITTLE EVOLUTION SINCE z ≈ 4 [PDF]

, 2013
Simone M. Weinmann, Marijn Franx, Pieter van Dokkum, Rachel Bezanson   +3 more
openalex   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

THENuSTAREXTRAGALACTIC SURVEY: FIRST DIRECT MEASUREMENTS OF THE ≳10 keV X-RAY LUMINOSITY FUNCTION FOR ACTIVE GALACTIC NUCLEI ATz> 0.1 [PDF]

, 2015
J. Aird, D. M. Alexander, D. R. Ballantyne, F. Civano, A. Del-Moro, R. C. Hickox, G. B. Lansbury, J. R. Mullaney, F. E. Bauer, W. N. Brandt, A. Comastri, A. C. Fabian, P. Gandhi, F. A. Harrison, B. Luo, D. Stern, E. Treister, L. Zappacosta, M. Ajello, R. Assef, M. Baloković, S. E. Boggs, M. Brightman, F. E. Christensen, W. W. Craig, M. Elvis, K. Forster, B. W. Grefenstette, C. J. Hailey, M. Koss, S. M. LaMassa, K. K. Madsen, S. Puccetti, C. Saez, C. M. Urry, D. R. Wik, W. Zhang   +36 more
openalex   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

A Novel Peak-Shape Aware Approach for Mass Alignment in Mass Spectrometry. [PDF]

Rapid Commun Mass Spectrom
Vanhemel T, Nijs M, Birmpili A, Hendriks TFE, Cuypers E, De Moor B.   +5 more
europepmc   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Associations of Dietary Decanoic Acid Intake With Cognitive Function in the Elderly and the Mediating Effects of Hypertension and Diabetes: An Analysis From NHANES 2011-2014. [PDF]

Brain Behav
Zhu H, Fu Q, Hu J, Wu Y, Min J.
europepmc   +1 more source