Results 131 to 140 of about 9,354,588 (295)

Jakość życia u chorych z jadłowstrętem psychicznym – badanie przeglądowe

open access: yes, 2018
Wstęp: Zaburzenia odżywiania są jednostką kryterialną charakteryzującą się niewystarczającym lub nadmiernym wzorcem odżywiania czy też lękiem związanym z wyglądem własnego ciała. Jedną z ich postaci jest jadłowstręt psychiczny.
Anna Żmijowska   +3 more
core   +1 more source

Association between the geriatric nutritional risk index and cognitive functions in older adults: a cross-sectional study from National Health and Nutrition Examination Survey

open access: yesFrontiers in Nutrition
ObjectiveTo investigate the associations between the geriatric nutritional risk index (GNRI) with cognitive functions among U.S. older adults. (Patients were classified into two nutrition risk groups based on the GNRI).MethodsOur analysis utilized data ...
Zhichun Tan, Yaxin Nie, Ning Yan
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

M/Z Value Calculator

open access: yes, 2014
Peptoids are peptide-mimicking polymers. In theory, a charged peptoid backbone can break into small fragments systemically following chemical bonds.
Adlakha, Ankit
core  

Experiences using Z animation tools. [PDF]

open access: yes, 2001
In this paper we describe our experience of using three different animation systems. We searched for and decided to use these tools in the context of a project which involved developing formal versions (in Z) of informal requirements documents, and then ...
Reeves, Steve, Reeve, Greg
core  

A simple approach to derive Z-score of reference change value involving more than two serial results (Letter)

open access: yes, 2015
The reference change value (RCV), also known as the critical difference, can be defined as the smallest difference required before two sequential laboratory results are considered significantly different (at a predefined confidence level), after taking ...
Loh, Tze Ping   +3 more
core   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

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