Results 31 to 40 of about 55,428 (190)

Switching disease‐modifying therapies in patients with spinal muscular atrophy: A systematic review on effectiveness outcomes

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
With multiple disease‐modifying therapies now available, treatment switching has become an important clinical consideration in the management of spinal muscular atrophy (SMA). While some switches are prompted by suboptimal clinical response, more commonly they are driven by treatment burden, convenience, or adverse events.
Andrej Belančić   +4 more
wiley   +1 more source

Trends in 25 years of antihypertensive agent utilization in Croatia – an alert for scientific community and healthcare providers

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Hypertension is a leading modifiable risk factor for cardiovascular mortality worldwide. This study aimed to evaluate 25‐year trends in antihypertensive agent (AHA) utilization in Croatia between 2000 and 2024. Methods We conducted a national, population‐based analysis using IMS and IQVIA pharmaceutical databases.
Andrej Belančić   +4 more
wiley   +1 more source

To the "Immortal composer": on the reception of Mozart's operas in 19th-century Zagreb

open access: yesDe Musica Disserenda, 2015
Mozart’s operas Don Giovanni and Die Zauberflöte were staged in Zagreb only from the 1830s. The paper deals with their reception through the analysis of critical reviews of Mozart’s operas in major 19th-century Zagreb newspapers within the context of the
Vjera Katalinić
doaj   +1 more source

Nonadherence and uncontrolled arterial hypertension in Croatia—Insights from the May Measurement Month 2023 campaign and Hunting the silent killer programme

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims To determine the prevalence of non‐adherence to antihypertensive medicines and to identify demographic and behavioral factors associated with non‐adherence in subjects enrolled in the May Measurement Month (MMM) 2023, as part of the permanent public health action Hunting the silent killer.
Valerija Bralić Lang   +12 more
wiley   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić   +7 more
wiley   +1 more source

Revitalization Paths Of Urban Centers: Tentative Observational Comparison Of Two Cities – Ljubljana And Zagreb [PDF]

open access: yesDružboslovne Razprave, 2019
In this paper, a comparison is made between two post-socialist countries (Slovenia and Croatia), namely, their capital cities (Ljubljana and Zagreb). The research aims to establish the main principles and difficulties of revitalisation in each city and ...
Jelena Zlatar Gamberožić
doaj  

Cost‐utility analysis of nusinersen–risdiplam switch in patients with spinal muscular atrophy in Croatia: A discrete event simulation model

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Introduction In recent years, the treatment of spinal muscular atrophy (SMA), a rare disease, has significantly progressed, improving patients' survival and overall quality of life. However, current SMA treatments are expensive, and some (nusinersen) are very inconvenient for patients.
Andrej Belančić   +4 more
wiley   +1 more source

Zagreb v omrežju evropskih mest

open access: yesDela, 2004
Članek prikazuje pomembnost Zagreba v okviru evropskih mest. Prikazana je primerjava demografskega razvoja Zagreba in drugih večjih evropskih mest. Analiziran je tudi položaj Zagreba na stiku Srednje in Jugovzhodne Evrope, še posebej v procesu evropske ...
Dražen Njegač
doaj   +1 more source

Potez triju trgova (Trg hrvatskih velikana – Trg žrtava fašizma – Krešimirov trg) – urbani status istočne ekstenzije zagrebačkoga Donjeg grada

open access: yesRadovi Instituta za Povijest Umjetnosti, 2020
Detaljno se predstavlja urbanistički i arhitektonski razvoj istočnoga gradskog središta, čiju okosnicu čini potez triju trgova: Trga hrvatskih velikana, Trga žrtava fašizma i Krešimirova trga.
Darja Radović Mahečić
doaj   +1 more source

The evolving therapeutic landscape of spinal muscular atrophy – A scoping review of investigational agents, emerging delivery technologies and strategic innovations

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Spinal muscular atrophy (SMA) is a severe neuromuscular disease with emerging therapeutic complexity. This review aims to systematically map the global pipeline of investigational treatments for SMA. Using ClinicalTrials.gov and complementary international registries, we identified 21 planned or ongoing interventional trials from 2020 to 2025 targeting
Andrej Belančić   +7 more
wiley   +1 more source

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