Results 161 to 170 of about 419,255 (408)
Abnormal photoreceptor outer segment development and early retinal degeneration in kif3a mutant zebrafish [PDF]
, 2016 Photoreceptors are highly specialized sensory neurons that possess a modified primary cilium called the outer segment. Photoreceptor outer segment formation and maintenance require highly active protein transport via a process known as intraflagellar ...
Akhtar +44 more
core +2 more sources
Advanced Science, EarlyView.The N1 peptide specifically targets neurons, enabling cytosolic delivery of fluorescent dyes and proteins for super‐resolution imaging and functional genetic modification. Abstract Efficient delivery of biomolecules into neurons has significant impacts on therapeutic applications in the central nervous system (CNS) and fundamental neuroscience research.
Xiaoqian Ge +16 more
wiley +1 more source
arXiv, 2010 The Zebrafish Model Organism Database (ZFIN) provides a Web resource of zebrafish genomic, genetic, developmental, and phenotypic data. Four different ontologies are currently used to annotate data to the most specific term available facilitating a better comparison between inter-species data.
arxiv
Evidence linking exposure of fish primary macrophages to antibiotics activates the NF-kB pathway. [PDF]
, 2020 Low doses of antibiotics are ubiquitous in the marine environment and may exert negative effects on non-target aquatic organisms. Using primary macrophages of common carp, we investigated the mechanisms of action following exposure to several common ...
Chen, Qiqing +8 more
core
Reconstructing Three‐Dimensional Optical Anisotropy with Tomographic Müller‐Polarimetric Microscopy
Advanced Science, EarlyView.Tomographic Müller polarimetric microscopy is a novel imaging technique that resolves 3D birefringent properties of bulky samples, unveiling hierarchical nanostructures at microscopic resolution. Based on incoherent visible‐light polarimetry, it achieves experimental simplicity by eliminating phase measurements.
Yang Chen +4 more
wiley +1 more source
On Zebrafish Disease Models and Matters of the Heart
Biomedicines, 2019 Coronary artery disease (CAD) is the leading form of cardiovascular disease (CVD), which is the primary cause of mortality worldwide. It is a complex disease with genetic and environmental risk factor contributions.
Panagiota Giardoglou, Dimitris Beis
doaj +1 more source
Cug2 is essential for normal mitotic control and CNS development in zebrafish. [PDF]
, 2011 Background: We recently identified a novel oncogene, Cancer-upregulated gene 2 (CUG2), which is essential for kinetochore formation and promotes tumorigenesis in mammalian cells.
Ahn, DG +8 more
core +2 more sources
EFTUD2 Regulates Cortical Morphogenesis via Modulation of Caspase‐3 and Aifm1 Splicing Pathways
Advanced Science, EarlyView.EFTUD2, a spliceosomal GTPase linked to MFDM, regulates cortical development through apoptotic control. Conditional Eftud2 knockout in murine neural stem cells induces microcephaly and cortical disorganization, while pathogenic variants drive neuronal loss.
Liping Chen +12 more
wiley +1 more source
Evolving technology: creating kidney organoids from stem cells
AIMS Bioengineering, 2016 The kidney is a complex organ whose excretory and regulatory functions are vital for maintaining homeostasis. Previous techniques used to study the kidney, including various animal models and 2D cell culture systems to investigate the mechanisms of renal
Bridgette E. Drummond +3 more
doaj +1 more source
Advanced Science, EarlyView.To address the problem of off‐target movement and low bioavailability of pesticides, two anisotropic supramolecular building units (BiTA18@β‐CD and BiTA18@γ‐CD) have been invented that can self‐assemble into nano‐sized hexagonal cuboids on the rice microcrystalline matrix. This manipulation realizes the enhanced utilization of bactericides for rice and
Run Yang +4 more
wiley +1 more source