Results 351 to 360 of about 419,255 (408)

Blueprints for healing: central nervous system regeneration in zebrafish and neonatal mice. [PDF]

BMC Biol
Cellini BR, Edachola SV, Faw TD, Cigliola V.   +3 more
europepmc   +1 more source

Metabolomics Assessment of the Mitigation of Lead‐Induced Inflammation in Adult Zebrafish (Danio rerio) by a Fermented Soybean Extract

Food Safety and Health, EarlyView.
Fermented soybean extract (FSE) at 50 mg/L has the potential to mitigate lead (Pb) toxicity (5 mg/L) observed in the zebrafish model. This study offers insights into food intervention in toxicology. ABSTRACT This study investigated the potential of fermented soybean extract (FSE) as an alternative therapy for lead (Pb) toxicity, without chelation side ...
Siok‐Geok Chong, Intan Safinar Ismail
wiley   +1 more source

Treatment of overactive K_ATP channels with glibenclamide in a zebrafish model and a clinical trial in humans with Cantú syndrome. [PDF]

Sci Rep
Kleinendorst L, Siegelaar SE, Roessler HI, Meiwand L, van den Boogaard M, de Bruin-Bon RHACM, van Duinen KF, Planken RN, Jaspars EH, Kemperman PMJH, Bouma BJ, Nichols CG, Bekkenk MW, van Haaften GW, van Haelst MM.   +14 more
europepmc   +1 more source

Oligodendrogenesis in Evolution, Development and Adulthood

Glia, EarlyView.
Oligodendrocytes and myelin took shape in jawed vertebrates. During development, OPCs are originated from NSCs and then undergo differentiation into mature oligodendrocytes that supply myelin. OPCs persist in the adult CNS and continue to produce oligodendrocytes and myelin. Adaptive myelination, which fine‐tunes neural circuits in response to neuronal
Hao Hu, Tianhao Gao, Jingwei Zhao, Huiliang Li   +3 more
wiley   +1 more source

Anti-inflammatory effect and mechanism of stytontriterpene D on RAW264.7 cells and zebrafish. [PDF]

Front Pharmacol
Yu C, Qiu G, Liu X, Xie Q, Lin Z, Wang F, Cai L.   +6 more
europepmc   +1 more source

Cordycepin mediates neuroprotection against apoptosis via ERK/CREB signaling activation in Aβ1–42‐induced neuronal cell models

Ibrain, Volume 11, Issue 1, Page 84-97, Spring 2025.
This study demonstrates cordycepin's neuroprotective effects against Aβ1–42‐induced apoptosis in neuronal cells, mediated through the activation of the extracellular signal‐regulated kinase/cyclic AMP‐responsive element‐binding protein (ERK/CREB) signaling pathway.
Wenshu Zhou, Cheng Wang, Yige Tan, Philip Lazarovici, Xiaoyan Wen, Shaoping Li, Wenhua Zheng   +6 more
wiley   +1 more source

Experimental PTSD Models in Zebrafish: A Systematic Review of Behavioral, Neurochemical, and Molecular Outcomes. [PDF]

Biology (Basel)
Sarapultsev A, Gusev E, Hu D, Komelkova M.   +3 more
europepmc   +1 more source

Patient‐derived xenograft models in pan‐cancer: From bench to clinic

Interdisciplinary Medicine, EarlyView.
Abstract Patient‐derived xenograft (PDX) models provide a robust preclinical platform that preserves the genetic and phenotypic heterogeneity of patient tumors while mirroring their tumor genetic characteristics, which retain malignant cells and the tumor pathological structure, making them valuable for studying tumor progression and developing ...
Jiatong Li, Ao Gu, Nannan Tang, Gokhan Zengin, Meng‐Yao Li, Yingbin Liu   +5 more
wiley   +1 more source

Pyriproxyfen Disrupts the Ongoing Spermatogenesis Wave in Danio rerio Potentially Mediated by Voltage‐Dependent Calcium Channels and Protein Kinase C

Journal of Applied Toxicology, EarlyView.
ABSTRACT Pyriproxyfen (PPX) is an analog of the juvenile hormone from insects. Following our previous studies, for the ex vivo short‐term effect, we chose 10−9 M pyriproxyfen to analyze the morphology of spermatogenesis wave cells. In silico docking and ADMET (Absorption, Distribution, Metabolism, Excretion, Toxicity) studies were carried out to ...
Bruna Antunes Zaniboni, Vanessa Staldoni de Oliveira, Gabriel Adan Araujo Leite, Valdelúcia Maria Alves de Souza Grinevicius, Rozangela Curi Pedrosa, Fátima Regina Mena Barreto Silva   +5 more
wiley   +1 more source