Results 71 to 80 of about 5,304,242 (286)

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Research on single-phase grounding characteristics of low-resistance grounding systems with distributed generation

open access: yesInternational Journal of Electrical Power & Energy Systems
The network-level characteristics of zero-sequence currents during single-phase ground faults in existing low-resistance grounding systems with inverter-interfaced distributed generators (IIDGs) remain unclear. Moreover, the influence of IIDG integration
Jianwen Zhao, Fuyang Zeng
doaj   +1 more source

INSTABILITY PROBLEM OF CONVENTIONAL TRANSFORMER DIFFERENTIAL PROTECTION-APPLICATION OF ZERO SEQUENCE CURRENT TRAP

open access: yes, 2013
Zero sequence component of current usually causes instability of the differential protection. It enters circuits through earthed terminals. The traditional way of solving the problem in differential schemes is by connecting the interposing current ...
Ezechukwu O A.
core   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

A voltage detection method based on dq transformation and symmetric component method

open access: yesGong-kuang zidonghua, 2018
In view of problem that fault type and phase of asymmetric voltage sag could not be quickly identified by traditional voltage sag detection algorithm, a voltage detection method based on dq transformation and symmetric component method was proposed ...
WANG Jianyu
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Modeling of PMSMs Considering Spatial Harmonics, Interturn Short-Circuit Faults, and Zero-Sequence Components

open access: yesIEEE Transactions on Industry Applications
This paper presents a rotor-position dependent (RPD) model for permanent-magnet synchronous machines (surface-mounted or interior permanent-magnet) considering both space harmonics, interturn short-circuit faults and zero-sequence components. First, the healthy machine model is obtained.
Geoffrey Postal   +2 more
openaire   +2 more sources

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

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