Results 41 to 50 of about 38,613 (267)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
JMIR Medical EducationBackgroundWhile artificial intelligence (AI)–generated feedback offers significant potential to overcome constraints on faculty time and resources associated with providing personalized feedback, its perceived usefulness can be ...
Hisaya Sudo +2 more
doaj +1 more source
Will It Zero-Shot?:Predicting Zero-Shot Classification Performance for Arbitrary Queries
2025 IEEE International Conference on Data Mining Workshops (ICDMW)Vision-Language Models like CLIP create aligned embedding spaces for text and images, making it possible for anyone to build a visual classifier by simply naming the classes they want to distinguish. However, a model that works well in one domain may fail in another, and non-expert users have no straightforward way to assess whether their chosen VLM ...
Kevin Robbins +6 more
openaire +2 more sources
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
SAVE: Self-Attention on Visual Embedding for Zero-Shot Generic Object Counting
Journal of ImagingZero-shot counting is a subcategory of Generic Visual Object Counting, which aims to count objects from an arbitrary class in a given image. While few-shot counting relies on delivering exemplars to the model to count similar class objects, zero-shot ...
Ahmed Zgaren +2 more
doaj +1 more source
Advances in Neural Information Processing Systems 37Language models (LMs) are bound to their tokenizer, which maps raw text to a sequence of vocabulary items (tokens). This restricts their flexibility: for example, LMs trained primarily on English may still perform well in other natural and programming languages, but have vastly decreased efficiency due to their English-centric tokenizer.
Minixhofer, Benjamin +2 more
openaire +4 more sources
Cross-Modal Zero-Shot Hashing [PDF]
2019 IEEE International Conference on Data Mining (ICDM), 2019 Hashing has been widely studied for big data retrieval due to its low storage cost and fast query speed. Zero-shot hashing (ZSH) aims to learn a hashing model that is trained using only samples from seen categories, but can generalize well to samples of unseen categories.
Xuanwu Liu +5 more
openaire +2 more sources
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source