Results 31 to 40 of about 8,777,763 (297)

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Optimized switching control strategy for current-fed half-bridge converter

open access: yes, 2014
A switching control strategy is proposed for current-fed half-bridge converters. An active switch based voltage doubler circuit at the secondary side of the isolation transformer is used to obtain zero-current-switching at turn-off and zero-voltage ...
Nayanasiri, D.R.   +5 more
core   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

open access: yesMolecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi   +2 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Design of a soft-switched interleaved high step-up non-isolated DC-DC converter for renewable energy sources integration

open access: yesScientific Reports
This study introduces an interleaved high step-up non-isolated DC-DC converter which incorporates a soft-switching mechanism. The proposed design ensures that all the switches and diodes operate under soft-switching conditions, specifically operating ...
Fatemeh Falahi   +3 more
doaj   +1 more source

An Interleaved Zero-Voltage Zero-Current Switching High Step-Up DC-DC Converter

open access: yesIEEE Access, 2021
An interleaved zero-voltage zero-current switching (ZVZCS) high step-up DC-DC converter is proposed for modern photovoltaic power generation systems. The proposed converter can achieve high voltage conversion gain without operating under extreme duty ...
Binxin Zhu   +3 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

Improved Interleaved DC-DC Converter Without Auxiliary Switches: Analysis and Experimental Validation

open access: yesElectrica
This paper presents a new two-phase interleaved boost converter for photovoltaic applications. An interleaved boost converter improved with an additional resonant circuit is proposed.
Veera Venkata Subrahmanya Kumar Bhajana   +3 more
doaj   +1 more source

A Hybrid Resonant ZVZCS Three-Level Converter Suitable for Photovoltaic Power DC Distribution System

open access: yesIEEE Access, 2020
A novel hybrid resonant zero-current- switching (ZCS) three-level DC-DC converter based on a dual transformer with two output filter capacitors is proposed in this paper, which is suitable for application in distributed photovoltaic power generation at ...
Syed Waqar Azeem   +4 more
doaj   +1 more source

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