Results 81 to 90 of about 3,656,389 (294)

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

An approximation algorithm for zero forcing

open access: yesDiscrete Applied Mathematics
We give an algorithm that finds a zero forcing set which approximates the optimal size by a factor of $\text{pw}(G)+1$, where $\text{pw}(G)$ is the pathwidth of $G$. Starting from a path decomposition, the algorithm runs in $O(nm)$ time, where $n$ and $m$ are the order and size of the graph, respectively.
Ben Cameron   +3 more
openaire   +2 more sources

Pilot-Assisted OFDM for Underwater Acoustic Communication

open access: yesJournal of Marine Science and Engineering, 2021
Multicarrier techniques have made it possible to wirelessly transmit data at higher rates for underwater acoustic (UWA) communication. Several multicarrier techniques have been explored in the past for wireless data transmission.
Mohsin Murad   +2 more
doaj   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Downlink Spectral Efficiency of Cell-Free Massive MIMO with Full-Pilot Zero-Forcing [PDF]

open access: yesIEEE Global Conference on Signal and Information Processing, 2018
Cell-free Massive multiple-input multiple-output (MIMO) ensures ubiquitous communication at high spectral efficiency (SE) thanks to increased macro-diversity as compared cellular communications.
Giovanni Interdonato   +3 more
semanticscholar   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Cell-free massive MIMO: Zero forcing and conjugate beamforming receivers

open access: yesJournal of Communications and Networks, 2019
In this paper, the uplink performance of cell-free massive multi-input multi-output (mMIMO) system with the zero-forcing (ZF) and conjugate beamforming (CB) receivers is investigated.
Yao Zhang   +3 more
semanticscholar   +1 more source

On the Uplink Throughput of Zero Forcing in Cell-Free Massive MIMO With Coarse Quantization [PDF]

open access: yesIEEE Transactions on Vehicular Technology, 2018
The recently proposed cell-free massive multiple input multiple output (MIMO) architecture is studied for the uplink. In contrast to most previous works, joint detection is performed using global channel state information (CSI).
Dick Maryopi, M. Bashar, A. Burr
semanticscholar   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi   +19 more
wiley   +1 more source

Sum Rate Analysis for Precoder Design in Distributed MIMO Systems Over Composite Fading Channels

open access: yesIEEE Access, 2018
In this paper, we consider the distributed multiple-input multiple-output systems which experience both the small-scale and large-scale fading. By employing the Rayleigh-lognormal model to characterize the composite fading channels, we derive the uplink ...
Li Wang   +4 more
doaj   +1 more source

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