Results 41 to 50 of about 564,129 (313)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Orthogonal polynomials on radial rays in the complex plane were introduced and studied intensively in several papers almost three decades ago. This paper presents an account of such kinds of orthogonality in the complex plane, as well as a number of new ...
Gradimir V. Milovanović
doaj +1 more source
The equivalence of zero span and zero semispan [PDF]
In this paper we introduce the idea of the symmetric span of a continuum, and show that continua with zero symmetric span are in class W W . Continua with zero span have zero symmetric span, but the converse does not hold. We also show that if every subcontinuum of the continuum M M is in class W W ...
openaire +1 more source
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
On the Zeros of Polynomials with Restricted Coefficients
Let P(z)=∑j=0najzjP\left( z \right) = \sum\nolimits_{j = 0}^n {{a_j}{z^j}} be a polynomial of degree n such that an ≥ an−1 ≥ . . . ≥ a1 ≥ a0 ≥ 0. Then according to Eneström-Kakeya theorem all the zeros of P (z) lie in |z| ≤ 1.
Zargar B. A., Gulzar M. H., Ali M.
doaj +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Lee-Yang zeros and phase transitions in nonequilibrium steady states
We consider how the Lee-Yang description of phase transitions in terms of partition function zeros applies to nonequilibrium systems. Here one does not have a partition function, instead we consider the zeros of a steady-state normalization factor in the
B. Derrida +17 more
core +1 more source
The meaning of net zero and how to get it right [PDF]
Samuel Fankhauser +14 more
openalex +1 more source
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Transcendentality of zeros of higher dereivatives of functions involving Bessel functions
C.L. Siegel established in 1929 [Ges. Abh., v.1, pp. 209-266] the deep results that (i) all zeros of Jv(x) and J′v(x) are transcendental when v is rational, x≠0, and (ii) J′v(x)/Jv(x) is transcendental when v is rational and x algebraic.
Lee Lorch, Martin E. Muldoon
doaj +1 more source

