Results 51 to 60 of about 572,970 (312)

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

The limiting Kac random polynomial and truncated random orthogonal matrices

open access: yes, 2010
An exact calculation of the eigenvalue statistics of truncated random Haar distributed real orthogonal matrices has recently been carried out by Khoruzhenko, Sommers and Zyczkowski.
Forrester, Peter J.
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Transcendentality of zeros of higher dereivatives of functions involving Bessel functions

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1995
C.L. Siegel established in 1929 [Ges. Abh., v.1, pp. 209-266] the deep results that (i) all zeros of Jv(x) and J′v(x) are transcendental when v is rational, x≠0, and (ii) J′v(x)/Jv(x) is transcendental when v is rational and x algebraic.
Lee Lorch, Martin E. Muldoon
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Generalized Predictive Control with Added Zeros and Poles in Its Augmented Model for Power Electronics Applications

open access: yesEnergies
Generalized predictive control (GPC) became one of the most popular and useful control strategies for academic and industry applications. An augmented model is applied to predict the future plant responses.
Raymundo Cordero   +2 more
doaj   +1 more source

Statistics or biology: the zero-inflation controversy about scRNA-seq data

open access: yesGenome Biology, 2022
Researchers view vast zeros in single-cell RNA-seq data differently: some regard zeros as biological signals representing no or low gene expression, while others regard zeros as missing data to be corrected.
Ruochen Jiang   +3 more
doaj   +1 more source

Lee-Yang zeros and phase transitions in nonequilibrium steady states

open access: yes, 2002
We consider how the Lee-Yang description of phase transitions in terms of partition function zeros applies to nonequilibrium systems. Here one does not have a partition function, instead we consider the zeros of a steady-state normalization factor in the
B. Derrida   +17 more
core   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

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