Results 91 to 100 of about 8,632,445 (288)

Biomimetic Core–Shell Liposome Nanoparticles Deplete Lipoproteins and Enhance the Purity of Extracellular Vesicles from Human Blood

Advanced Functional Materials, EarlyView.
Lipoprotein‐mimicking nanoparticles (SL‐NPs), comprising Fe3O4@SiO2 cores coated with liposomal bilayers, selectively capture lipoproteins through protein corona formation. The resulting SL‐NP‐lipoprotein complexes can be removed by low‐speed centrifugation, thereby enhancing the purity of small extracellular vesicles (sEVs) isolated from human serum ...
Man‐Di Wang, Andrew J. Perciaccante, David Inman, Bong Hwan Sung, Alissa M. Weaver, Suzanne M. Ponik, Ying Ge, Song Jin   +7 more
wiley   +1 more source

Myogenic Fusogen‐Engineered Lipid Nanoparticles Enhance mRNA Delivery in Skeletal Muscle

Advanced Functional Materials, EarlyView.
This study reports a biomimetic strategy of engineering full‐length Myomaker, a muscle‐specific fusogen, into lipid nanoparticles (LNPs) to harness the native myoblast fusion capability for skeletal muscle mRNA delivery. The resulting Mymk‐LNPs enhance transfection in differentiating myocytes and enable Cre‐mediated reporter activation in injured ...
Fangyu Zhang, Zhisheng Xu, Yaou Duan, Yehui Sun, Shiying Wu, Tao Long, Mateusz Durbacz, Li Zhang, Yufen Xiao, Yu‐Chung Pien, Erick D. Guerrero, Zeru Tian, Xu Wang, Pratima Basak, Sumanta Chatterjee, Ning Liu, Xiaochun Li, Eric N. Olson, Daniel J. Siegwart   +18 more
wiley   +1 more source

Investigating the relative adsorption of polymeric depressants on pure minerals [PDF]

, 2011
The aim of this study was to investigate the relative adsorption of polymeric depressants on pure minerals. The minerals used were talc, pyroxene, plagioclase, chromite and chalcopyrite and the depressants used were guar gum and carboxymethyl cellulose ...
Mhlanga, Sabatha Sanele
core   +1 more source

Influence of Metal Oxide Nanoparticles Concentration on their Zeta Potential

, 2014
In an attempt to estimate the zeta potential of various metal oxide nanoparticles (NPs) dispersed in water, it is interesting to observe that both the magnitude and the sign of this property depend highly upon their concentration.
Wang, Nan; Hsu, Chien; Zhu, Lihua; Tseng, Shiojenn; Hsu, Jyh-Ping
core   +1 more source

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

Advanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal, Younan Ma, Asad Khanmohammed, Dipen Parande, Hanming Zhang, Saket Dolare, Juliet Chen, Apiwat Wangweerawong, Saswata Karmakar, Hongfeng Deng, Frank Koppenhagen, Shraddha Sharma, Eric Reyes, Sherry He, Lianne Boeglin, Caroline Woo, Azadeh Paksa, Ayed Allawzi, Anusha Dias, Gregory Troiano, Shrirang Karve, Frank DeRosa   +21 more
wiley   +1 more source

Diffusiophoresis and diffusioosmosis in a junction device with a long microchannel: colloid dynamics and particle characterisation

Flow
The dynamics of carboxyl-modified polystyrene colloidal particles of varying size and zeta potential were investigated in a microfluidic junction device where merging electrolyte streams generated a steady-state salt concentration gradient.
Christina Puijk, Adnan Chakra, Goran T. Vladisavljević, Guido Bolognesi   +3 more
doaj   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

SYNTHESIS AND CHARACTERIZATION OF DRUG DELIVERY SYSTEM FOR LOADING SPIRULINA USING CHITOSAN NANOPARTICLES [PDF]

Assiut Veterinary Medical Journal
Chitosan, a chitin-derived biopolymer, is garnering significant academic interest due to its distinctive properties and diverse applications. Spirulina-loaded chitosan nanoparticles demonstrate enhanced antioxidant, antimicrobial, and wound-healing ...
RASHA AL-GHAZALY, HAWRAA NAJI, ADNAN JASSIM, ESSA ALHTHEAL   +3 more
doaj   +1 more source

A Magneto‐Mechanically Activated Nerve Guidance Conduit Promotes Peripheral Nerve Regeneration via TIMP1‐Mediated Membrane Tension Transfer

Advanced Functional Materials, EarlyView.
This study presents a magneto‐mechanical strategy that incorporates FP@MSCs into an aligned PCL/GelMA nerve guidance conduit. Magnetic stimulation increases membrane tension in FP@MSCs, triggering cytoskeletal remodeling, Schwann cell‐like differentiation, and TIMP1 secretion. TIMP1 activates ITGB1/CD63–FAK signaling in NE‐4C cells, increasing membrane
Xinyu Zhu, Yumin Wu, Xiang Gao, Tianlu Wang, Wanting Jia, Xueying Mei, Huanzhong Ji, Zongxi Wu, Yujie Liang, Xiang Li, Kan Li, Jingyuan Li, Guangsen Zheng, Guiqing Liao, Siyong Gao   +14 more
wiley   +1 more source

Impact of Zeta Potential on Copper Adsorption of Surface-Modified Hydroxyapatites Derived From Fish Bone Waste

Acta Natura et Scientia
Zeta potential emerges as a crucial parameter in understanding particle surface charges and assessing the stability of colloidal systems. It also serves as a key indicator in determining electrostatic interactions between surfaces and ions.
Bayram Kızılkaya
doaj   +1 more source