Results 51 to 60 of about 3,384 (237)

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Evolutionary dynamics on a regular networked structured and unstructured multi‐population

International Journal of Robust and Nonlinear Control, EarlyView., 2023
Abstract In this paper, we study collective decision‐making in a multi‐population framework, where groups of individuals represent whole populations that interact by means of a regular network. Each group consists of a number of players and every player can choose between two options.
Wouter Baar, Leonardo Stella, Dario Bauso   +2 more
wiley   +1 more source

Delivery of Multifunctional Microspheres via Intravesical Instillation for Bladder Carcinoma: Therapeutic Potential and Mechanistic Insights

Advanced Healthcare Materials, EarlyView.
PCTM microspheres were successfully synthesized using microfluidic and click chemistry techniques.In Vivo and in vitro experiments have shown that PCTM microspheres have obvious targeting, adhesion, membrane penetration and anti‐tumor properties for bladder tumors.The antitumor mechanism of PCTM microspheres is to indirectly induce S‐stage blockage of ...
Zhaoxiang Lu, Wentie Yang, Youzhi Hong, Yusen Qiao, Chaozhao Liang   +4 more
wiley   +1 more source

Dual‐Functional Polyphosphoesters for Gene Delivery: Synergistic Effects of Guanidinium and Hydrophobic Side Chains in Degradable Polymers

Advanced Healthcare Materials, EarlyView.
This study presents guanidinium‐ and indole‐functionalized polyphosphoesters as degradable, non‐viral gene delivery vectors. Through precise tuning of charge density and hydrophobicity, these polymers form stable polyplexes with low toxicity. Remarkably, minor structural changes yield up to 200‐fold differences in transfection efficiency, highlighting ...
Markus Kötzsche, Andreas Dzierza, Jan Egger, Timo Rheinberger, Christin Weilandt, Frederik R. Wurm, Ivo Nischang, Dagmar Fischer, Kalina Peneva   +8 more
wiley   +1 more source

Comparative Analysis of Fourth-Order Non-Isolated DC-DC Converters: Ćuk, SEPIC and Zeta [PDF]

Journal of Electrical and Electronics Engineering
This paper presents a comparative study of three fourth-order non-isolated DC-DC converters: Ćuk, SEPIC, and Zeta. Analytical expressions for output voltage ripple were derived for each topology, and their accuracy was validated through numerical ...
ȘCHIOP Adrian, TRIP Daniel, ȘCHIOP Adrian Marian   +2 more
doaj  

From RNA to DNA: How Cargo Identity Reprograms Lipid Nanoparticle Architecture and Function

Advanced Healthcare Materials, EarlyView.
The evolution of lipid nanoparticles (LNPs) spans from RNA‐LNPs, used in mRNA vaccines, to DNA‐LNPs, ideal for gene therapies. Emerging bionano architectures, decorated with DNA and plasma proteins, pave the way for advanced DNA‐based therapies that are more stable, targeted, and customizable.
Erica Quagliarini, Daniela Pozzi, Giulio Caracciolo   +2 more
wiley   +1 more source

Topological Hochschild homology and zeta values

Duke Mathematical Journal
Using work of Antieau and Bhatt-Morrow-Scholze, we define a filtration on topological Hochschild homology and its variants $TP$ and $TC^-$ of quasi-lci rings with bounded torsion, which recovers the BMS-filtration after $p$-adic completion. Then we compute the graded pieces of this filtration in terms of Hodge completed derived de Rham cohomology ...
openaire   +3 more sources

An In Situ Embedded B‐MOF Sponge With Shape‐Memory for All‐in‐One Diabetic Wound Therapy

Advanced Healthcare Materials, EarlyView.
A smart shape‐memory sponge dressing (P1A3@B‐MOF) is developed for accelerated diabetic wound healing. It achieves pH‐responsive corelease of Zn2+ and salvianolic acid B, synergistically providing antibacterial action, repolarizing macrophages to the M2 phenotype, and promoting angiogenesis.
Hai Zhou, Chaoyang Huang, Yanqi Chen, Tingzi Zhao, Fengyi Zhu, Gong Jun, Jinrong Zhang, Yingsong Pan, Qiulan Wen, Lei Yang, Huihui Zhang, Lianglong Chen   +11 more
wiley   +1 more source

Finite temperature Casimir effect for a spinor field in cosmic dispiration spacetime

Journal of High Energy Physics
This study explores the finite temperature Casimir effect for a massive spinor field in cosmic dispiration spacetime, formed by the combination of a cosmic string and a screw dislocation, using the generalized zeta function regularization method.
Joás Venâncio, Herondy Mota, Azadeh Mohammadi   +2 more
doaj   +1 more source

Switched capacitor and coupled inductor based high power factor charger for E-2/E-3 wheelers

e-Prime: Advances in Electrical Engineering, Electronics and Energy
This paper introduces a modified Zeta converter topology designed specifically for charging low voltage electric vehicles (LVEVs), enhancing performance for electric two (E-2) and electric three (E-3) wheelers.
Aswin Dilip Kumar, Jitendra Gupta, Bhim Singh   +2 more
doaj   +1 more source